Results 21 to 30 of about 9,547,943 (379)
SSRN Electronic Journal, 2010 Awards are widespread in all countries and are prevalent both in the public sphere and in the private sector. This paper argues, and empirically supports, that awards serve public functions and economists should take them seriously. Using a unique cross-country data set, we suggest that awards serve as signals.
Frey, Bruno S, Neckermann, Susanne
openaire +7 more sources
Mechanodetection of neighbor plants elicits adaptive leaf movements through calcium dynamics
Nature Communications, 2023 Plants detect their neighbors via various cues, including reflected light and touching of leaf tips, which elicit upward leaf movement (hyponasty). It is currently unknown how touch is sensed and how the signal is transferred from the leaf tip to the ...
Chrysoula K. Pantazopoulou +7 more
doaj +1 more source
Inhibition of hypothalamic leukemia inhibitory factor exacerbates diet-induced obesity phenotype
Journal of Neuroinflammation, 2017 Background The consumption of large amounts of dietary fats can trigger an inflammatory response in the hypothalamus and contribute to the dysfunctional control of caloric intake and energy expenditure commonly present in obesity.
Milena Fioravante +8 more
doaj +1 more source
Nature Communications, 2022 Inducible disruption of TET dioxygenases in mouse embryonic stem cells results in chromosome mis-segregation and aneuploidies, due to Khdc3 downregulation suggesting a role for TET enzymes and DNA methylation patterns in maintaining genome stability.
Romain O. Georges +8 more
doaj +1 more source
PKCζ-Mitogen-Activated Protein Kinase Signaling Mediates Crotalphine-Induced Antinociception
Toxins, 2021 Crotalphine (CRP) is a structural analogue to a peptide that was first identified in the crude venom from the South American rattlesnake Crotalus durissus terrificus.
Bárbara G. de Freitas +6 more
doaj +1 more source
Compensatory effects in the PI3K/PTEN/AKT signaling network following receptor tyrosine kinase inhibition [PDF]
, 2011 Overcoming de novo and acquired resistance to anticancer drugs that target signaling networks is a formidable challenge for drug design and effective cancer therapy.
Bown, James L. +5 more
core +4 more sources
Therapeutic approaches targeting CD95L/CD95 signaling in cancer and autoimmune diseases
Cell Death and Disease, 2022 Cell death plays a pivotal role in the maintenance of tissue homeostasis. Key players in the controlled induction of cell death are the Death Receptors (DR).
Vesna Risso +2 more
doaj +1 more source
The Signal for Signaling, Found
PLoS Pathogens, 2009 An important task in the life of bacteria is to influence their environment, which for commensal, symbiotic, and pathogenic bacteria also includes their hosts. This is done primarily by secreting various sets of proteins (effectors), either simply to the outside environment or directly into host cells.
Marcin Grynberg, Adam Godzik
openaire +5 more sources
Cell Death Discovery, 2023 Spinal Muscular Atrophy (SMA) is a severe genetic neuromuscular disorder that occurs in childhood and is caused by misexpression of the survival motor neuron (SMN) protein.
Alba Sansa +6 more
doaj +1 more source
Inhibition of Food Intake by PACAP in the Hypothalamic Ventromedial Nuclei is Mediated by NMDA Receptors [PDF]
, 2014 Central injections of pituitary adenylate cyclase-activating polypeptide (PACAP) into the ventromedial nuclei (VMN) of the hypothalamus produce hypophagia that is dependent upon the PAC1 receptor; however, the signaling downstream of this receptor in the
Choi, Sujean +3 more
core +2 more sources