Results 11 to 20 of about 3,216,633 (318)

Signaling to Experts [PDF]

SSRN Electronic Journal, 2017
Abstract We study competitive equilibria in a signalling economy with heterogeneously informed buyers. In terms of the classic Spence (1973, The Quarterly Journal of Economics, 87, 355—374) model of job market signalling, firms have access to direct but imperfect information about worker types, in addition to observing their education ...
Kurlat, Pablo, Scheuer, Florian
openaire   +3 more sources

Signaling with costly acquisition of signals [PDF]

Journal of Economic Behavior & Organization, 2018
In this paper we investigate the consequences of introducing a cost to observe the signal in an otherwise standard signaling game. Beyond identifying equilibria, which we contrast with those of a standard signaling game, we study their robustness to two important classes of refinements: acting through restrictions on out-of-equilibrium beliefs and ...
Bilancini, Ennio, Boncinelli, Leonardo
openaire   +5 more sources

The Signal for Signaling, Found

PLoS Pathogens, 2009
An important task in the life of bacteria is to influence their environment, which for commensal, symbiotic, and pathogenic bacteria also includes their hosts. This is done primarily by secreting various sets of proteins (effectors), either simply to the outside environment or directly into host cells.
Marcin Grynberg, Adam Godzik
openaire   +4 more sources

Hedgehog Signaling in Cortical Development [PDF]

, 2023
The Hedgehog (Hh) pathway plays a crucial role in embryonic development, acting both as a morphogenic signal that organizes tissue formation and a potent mitogenic signal driving cell proliferation.
Xuecai Ge, Cai, Eva, Ge, Xuecai, Maximiliano Gonzalez Barba, Barba, Maximiliano Gonzalez, Eva Cai   +5 more
core   +1 more source

TGFbeta/BMP Signaling Pathway in Cartilage Homeostasis [PDF]

, 2019
Contains fulltext : 208575.pdf (Publisher’s version ) (Open Access)Cartilage homeostasis is governed by articular chondrocytes via their ability to modulate extracellular matrix production and degradation.
Caam, A.P.M. van, Thielen, N.G.M., Peter van der Kraan, Nathalie Thielen, Arjan van Caam, Kraan, P.M. van der   +5 more
core   +1 more source

Augmenting endogenous wnt signaling improves skin wound healing [PDF]

, 2013
Wnt signaling is required for both the development and homeostasis of the skin, yet its contribution to skin wound repair remains controversial. By employing Axin2(LacZ/+) reporter mice we evaluated the spatial and temporal distribution patterns of Wnt ...
Manzano Wilfred R., Fang Mark Y., Girija R Dhamdhere, Anthony E. Oro, Bo Liu, Fang, Mark Y, Whyte, Jemima L., Helms Jill A., Wilfred R. Manzano, Nick D. Evans (474290), Manzano, Wilfred R, Howard Y. Chang (215450), Smith, Andrew A, Manzano, Wilfred R., Whyte, Jemima L, Jemima L. Whyte (474287), Nick D Evans, Helms, Jill A., Andrew A Smith, Anthony E Oro, Andrew A. Smith (474288), Oro Anthony E., Chang, Howard Y., Jemima L Whyte, Liu Bo, Howard Y Chang, Dhamdhere, Girija R, Evans Nick D., Evans, Nick D., Wilfred R. Manzano (474289), Oro, Anthony E., Nick D. Evans¤a, Smith Andrew A., Whyte Jemima L., Liu, Bo, Mark Y. Fang (474292), Wilfred R Manzano, Jill A. Helms (25398), Fang, Mark Y., Smith, Andrew A., Andrew A. Smith, Evans, Nick D, Helms, Jill A, Girija R. Dhamdhere (474291), Girija R. Dhamdhere, Jill A Helms, Mark Y. Fang¤b, Anthony E. Oro (474293), Jill A. Helms, Dhamdhere, Girija R., Mark Y Fang, Chang, Howard Y, Chang Howard Y., Jemima L. Whyte, Oro, Anthony E, Howard Y. Chang, Bo Liu (127343), Dhamdhere Girija R.   +57 more
core   +2 more sources

A New Wave of Targeting ‘Undruggable’ Wnt Signaling for Cancer Therapy: Challenges and Opportunities

, 2023
Aberrant Wnt signaling activation is frequently observed in many cancers. The mutation acquisition of Wnt signaling leads to tumorigenesis, whereas the inhibition of Wnt signaling robustly suppresses tumor development in various in vivo models.
Woo-Jung Park, Moon Jong Kim
core   +1 more source

Awards as Signals [PDF]

SSRN Electronic Journal, 2010
Awards are widespread in all countries and are prevalent both in the public sphere and in the private sector. This paper argues, and empirically supports, that awards serve public functions and economists should take them seriously. Using a unique cross-country data set, we suggest that awards serve as signals.
Frey, Bruno S, Neckermann, Susanne
openaire   +5 more sources

Hedgehog and Gpr161: Regulating cAMP Signaling in the Primary Cilium

, 2020
Compartmentalization of diverse types of signaling molecules contributes to the precise coordination of signal propagation. The primary cilium fulfills this function by acting as a spatiotemporally confined sensory signaling platform.
Pia Aanstad, Omar Torres-Quesada, Philipp Tschaikner, Eduard Stefan, Florian Enzler   +4 more
core   +1 more source

Alternate transcription of the Toll-like receptor signaling cascade [PDF]

, 2006
Alternate splicing of key signaling molecules in the Toll-like receptor (Tlr) cascade has been shown to dramatically alter the signaling capacity of inflammatory cells, but it is not known how common this mechanism is. We provide transcriptional evidence
Kai, Chikatoshi, Forrest, A, Schroder, K, Forrest, Alistair, Kawai, J, Kawaji, H, Wells, Christine A, Faulkner, G, Carninci, P, Hume, DA, Carninci, Piero, Grimmond, SM, Himes, SR, Lo, Sandra, Schroder, Kate, Taylor, D, Grimmond, Sean M, Faulkner, Geoffrey, Kasukawa, T, Himes, S Roy, Kawai, Jun, Waddell, Nic, Hayashizaki, Yoshihide, Kasukawa, Takeya, Katayama, S, Hayashizaki, Y, Chalk, Alistair M, Katayama, Shintaro, Hume, David A, Chalk, AM, Taylor, Darrin, Kawaji, Hideya, Wells, CA, Waddell, N, Lo, S, Kai, C   +35 more
core   +1 more source