Results 11 to 20 of about 3,111,579 (318)

Hedgehog Signaling in Cortical Development [PDF]

, 2023
The Hedgehog (Hh) pathway plays a crucial role in embryonic development, acting both as a morphogenic signal that organizes tissue formation and a potent mitogenic signal driving cell proliferation.
Xuecai Ge, Cai, Eva, Ge, Xuecai, Maximiliano Gonzalez Barba, Barba, Maximiliano Gonzalez, Eva Cai   +5 more
core   +1 more source

Signaling to Experts [PDF]

SSRN Electronic Journal, 2017
Abstract We study competitive equilibria in a signalling economy with heterogeneously informed buyers. In terms of the classic Spence (1973, The Quarterly Journal of Economics, 87, 355—374) model of job market signalling, firms have access to direct but imperfect information about worker types, in addition to observing their education ...
Kurlat, Pablo, Scheuer, Florian
openaire   +3 more sources

Signaling with costly acquisition of signals [PDF]

Journal of Economic Behavior & Organization, 2018
In this paper we investigate the consequences of introducing a cost to observe the signal in an otherwise standard signaling game. Beyond identifying equilibria, which we contrast with those of a standard signaling game, we study their robustness to two important classes of refinements: acting through restrictions on out-of-equilibrium beliefs and ...
Bilancini, Ennio, Boncinelli, Leonardo
openaire   +5 more sources

The Signal for Signaling, Found

PLoS Pathogens, 2009
An important task in the life of bacteria is to influence their environment, which for commensal, symbiotic, and pathogenic bacteria also includes their hosts. This is done primarily by secreting various sets of proteins (effectors), either simply to the outside environment or directly into host cells.
Marcin Grynberg, Adam Godzik
openaire   +4 more sources

The Role of BANK1 in B Cell Signaling and Disease [PDF]

, 2021
The preparation of this review was funded by the Ministerio de Economia y Competitividad (now Ministerio de Ciencia e Innovacion) of the Government of Spain with number SAF2016-78631-P. G.G.H.
Gonzalo Gómez Hernández, María Morell, Gómez Hernández, Gonzalo, Alarcón Riquelme, Marta Eugenia, Morell Hita, María, Marta E. Alarcón-Riquelme   +5 more
core   +1 more source

Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling

, 2021
FGFR (fibroblast growth factor receptor) signaling controls fundamental processes in embryonic, fetal and adult human life. The magnitude, duration, and location of FGFR signaling must be strictly controlled in order to induce the correct biological ...
Wiedlocha, Antoni, Jørgen Wesche, Szybowska, Patrycja Maria, Michal Kostas, Antoni Wiedlocha, Patrycja Szybowska, Kostas, Michal Janusz, Wesche, Jørgen, Haugsten, Ellen Margrethe, Ellen Margrethe Haugsten   +9 more
core   +1 more source

TGFbeta/BMP Signaling Pathway in Cartilage Homeostasis [PDF]

, 2019
Contains fulltext : 208575.pdf (Publisher’s version ) (Open Access)Cartilage homeostasis is governed by articular chondrocytes via their ability to modulate extracellular matrix production and degradation.
Caam, A.P.M. van, Thielen, N.G.M., Peter van der Kraan, Nathalie Thielen, Arjan van Caam, Kraan, P.M. van der   +5 more
core   +1 more source

Alternate transcription of the Toll-like receptor signaling cascade [PDF]

, 2006
Alternate splicing of key signaling molecules in the Toll-like receptor (Tlr) cascade has been shown to dramatically alter the signaling capacity of inflammatory cells, but it is not known how common this mechanism is. We provide transcriptional evidence
Kai, Chikatoshi, Forrest, A, Schroder, K, Forrest, Alistair, Kawai, J, Kawaji, H, Wells, Christine A, Faulkner, G, Carninci, P, Hume, DA, Carninci, Piero, Grimmond, SM, Himes, SR, Lo, Sandra, Hume, David, Schroder, Kate, Taylor, D, Grimmond, Sean M, Faulkner, Geoffrey, Chalk, Alistair, Kasukawa, T, Himes, S Roy, Grimmond, Sean, Kawai, Jun, Waddell, Nic, Lo, Yu-Lan Sandra, Hayashizaki, Yoshihide, Kasukawa, Takeya, Wells, Christine, Katayama, S, Hayashizaki, Y, Chalk, Alistair M, Katayama, Shintaro, Hume, David A, Chalk, AM, Taylor, Darrin, Kawaji, Hideya, Wells, CA, Waddell, N, Lo, S, Kai, C   +40 more
core   +1 more source

Awards as Signals [PDF]

SSRN Electronic Journal, 2010
Awards are widespread in all countries and are prevalent both in the public sphere and in the private sector. This paper argues, and empirically supports, that awards serve public functions and economists should take them seriously. Using a unique cross-country data set, we suggest that awards serve as signals.
Frey, Bruno S, Neckermann, Susanne
openaire   +5 more sources

Acute deletion of TET enzymes results in aneuploidy in mouse embryonic stem cells through decreased expression of Khdc3

Nature Communications, 2022
Inducible disruption of TET dioxygenases in mouse embryonic stem cells results in chromosome mis-segregation and aneuploidies, due to Khdc3 downregulation suggesting a role for TET enzymes and DNA methylation patterns in maintaining genome stability.
Romain O. Georges, Hugo Sepulveda, J. Carlos Angel, Eric Johnson, Susan Palomino, Roberta B. Nowak, Arshad Desai, Isaac F. López-Moyado, Anjana Rao   +8 more
doaj   +1 more source