RIPK1 signaling pathways: implications for autoimmune and neuroinflammatory diseases. [PDF]
Front ImmunolPajulas A +3 more
europepmc +1 more source
Epidermal Growth Factor Induces Phosphorylation of Extracellular Signal-Regulated Kinase 2 via Multiple Pathways [PDF]
, 1993 Boudewijn Burgering +5 more
openalex +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Decoding Sepsis: Unraveling Key Signaling Pathways for Targeted Therapies. [PDF]
Research (Wash D C)Tang L +6 more
europepmc +1 more source
Signal transduction pathways leading to the production of IL-8 by human monocytes are differentially regulated by dexamethasone [PDF]
, 1992 Heli Anttila +3 more
openalex +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
Immunosenescence: signaling pathways, diseases and therapeutic targets. [PDF]
Signal Transduct Target TherFu Y +8 more
europepmc +1 more source
The mitogen-activated protein kinase signal transduction pathway
, 1993 Roger J. Davis
openalex +1 more source