Results 311 to 320 of about 2,211,530 (330)
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The Ethylene Signaling Pathway
Science, 2004Plants use a structurally very simple gas molecule, the hydrocarbon ethylene, to modulate various developmental programs and coordinate responses to a multitude of external stress factors. How this simple molecule generates such a diverse array of effects has been the subject of intense research for the past two decades.
Anna Stepanova, Jose M. Alonso
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Brassinosteroid Signaling Pathway
Science's STKE, 2006Plant growth is regulated by an intricate network of hormonal signaling pathways. These small-molecule hormones cause changes in gene expression that are associated with cell expansion and division and changes in development. Paradoxically, six of these hormones appear to have largely overlapping functions, yet the loss of response to any ...
Youssef Belkhadir +2 more
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Science's STKE, 2005
The structural simplicity of the plant hormone ethylene contrasts with its dramatic effects in various developmental processes, as well as in the cellular processes that ethylene initiates in response to a diversity of environmental signals. A single well-conserved signaling cascade mediates this broad spectrum of responses.
Anna Stepanova, Jose M. Alonso
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The structural simplicity of the plant hormone ethylene contrasts with its dramatic effects in various developmental processes, as well as in the cellular processes that ethylene initiates in response to a diversity of environmental signals. A single well-conserved signaling cascade mediates this broad spectrum of responses.
Anna Stepanova, Jose M. Alonso
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Crossroads of Signaling Pathways [PDF]
, 2013 As studies on PC progression continue to uncover a growing number of crosstalks and co-occurrences of mutations and epigenetic alterations, new drugs are getting approved bringing significant changes in the treatment paradigm of these tumors.
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Science's STKE, 2006
Jasmonates in plants are cyclic fatty acid–derived regulators structurally similar to prostaglandins in metazoans. These chemicals mediate many of plants' transcriptional responses to wounding and pathogenesis by acting as potent regulators for the expression of numerous frontline immune response genes, including those for defensins and ...
Robin Liechti +2 more
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Jasmonates in plants are cyclic fatty acid–derived regulators structurally similar to prostaglandins in metazoans. These chemicals mediate many of plants' transcriptional responses to wounding and pathogenesis by acting as potent regulators for the expression of numerous frontline immune response genes, including those for defensins and ...
Robin Liechti +2 more
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Seminars in Immunology, 2004
Toll-like receptors (TLRs) have been established to play an essential role in the activation of innate immunity by recognizing specific patterns of microbial components. TLR signaling pathways arise from intracytoplasmic TIR domains, which are conserved among all TLRs.
Kiyoshi Takeda, Shizuo Akira
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Toll-like receptors (TLRs) have been established to play an essential role in the activation of innate immunity by recognizing specific patterns of microbial components. TLR signaling pathways arise from intracytoplasmic TIR domains, which are conserved among all TLRs.
Kiyoshi Takeda, Shizuo Akira
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Signaling pathways in medulloblastoma
Journal of Cellular Physiology, 2008AbstractMedulloblastoma is the most common brain tumor of childhood. Multiple signaling pathways have been associated with medulloblastoma formation and growth. These include the developmental pathways Hedgehog, (Hh) Notch, and Wnt as well as the receptor tyrosine kinases (RTK) c‐Met, erbB2, IGF‐R and TrkC, and the oncoprotein Myc.
Roger Abounader +2 more
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Current Opinion in Biotechnology, 2019
The last decade has seen a rise in the development of methods and models to analyze cellular networks on all levels. The applications of this knowledge are, however, often confined to specifics of the network in concrete conditions and leveraging it is hampered by the lack of information about this context and its implications on the system.
Edda Klipp, Friedemann Uschner
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The last decade has seen a rise in the development of methods and models to analyze cellular networks on all levels. The applications of this knowledge are, however, often confined to specifics of the network in concrete conditions and leveraging it is hampered by the lack of information about this context and its implications on the system.
Edda Klipp, Friedemann Uschner
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Signaling and effector pathways
Current Opinion in Rheumatology, 1999There is increasing evidence that distinct signaling and effector pathways in the rheumatoid synovium result in a cascade of pathophysiologic events. These interactions, which finally lead to progressive joint destruction, are different from all other joint diseases in numerous aspects.
U, Müller-Ladner, R E, Gay, S, Gay
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Signaling pathways in phagocytosis
BioEssays, 1999Phagocytosis is an uptake of large particles governed by the actin-based cytoskeleton. Binding of particles to specific cell surface receptors is the first step of phagocytosis. In higher Eucaryota, the receptors able to mediate phagocytosis are expressed almost exclusively in macrophages, neutrophils, and monocytes, conferring immunodefence properties
Katarzyna Kwiatkowska, Andrzej Sobota
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