Results 1 to 10 of about 624,213 (299)

Adoption of Preventive Behaviour Strategies and Public Perceptions About COVID-19 in Singapore [PDF]

International Journal of Health Policy and Management, 2022
BackgroundThe unprecedented severity of coronavirus disease 2019 (COVID-19) constitutes a serious public health concern. However, adoption of COVID-19-related preventive behaviours remain relatively unknown.
Semra Ozdemir, Sean Ng, Isha Chaudhry, Eric Andrew Finkelstein   +3 more
doaj   +1 more source

Improved understanding of biorisk for research involving microbial modification using annotated sequences of concern

Frontiers in Bioengineering and Biotechnology, 2023
Regulation of research on microbes that cause disease in humans has historically been focused on taxonomic lists of ‘bad bugs’. However, given our increased knowledge of these pathogens through inexpensive genome sequencing, 5 decades of research in ...
Gene D. Godbold, F. Curtis Hewitt, Anthony D. Kappell, Matthew B. Scholz, Stacy L. Agar, Todd J. Treangen, Krista L. Ternus, Jonas B. Sandbrink, Gregory D. Koblentz   +8 more
doaj   +1 more source

skater: an R package for SNP-based kinship analysis, testing, and evaluation [version 1; peer review: 2 approved, 1 approved with reservations]

F1000Research, 2022
Motivation: SNP-based kinship analysis with genome-wide relationship estimation and IBD segment analysis methods produces results that often require further downstream process- ing and manipulation.
Bruce Budowle, Carlos Acevedo, Shakeel Jessa, August E. Woerner, Jianye Ge, Stephen D. Turner, Matthew Scholz, V.P. Nagraj   +7 more
doaj   +1 more source

Signature quantization [PDF]

Proceedings of the National Academy of Sciences, 2003
We associate to the action of a compact Lie group G on a line bundle over a compact oriented even-dimensional manifold a virtual representation of G using a twisted version of the signature operator. We obtain analogues of various theorems in the more standard theory of geometric quantization.
Guillemin, Victor, Sternberg, Shlomo, Weitsman, Jonathan   +2 more
openaire   +5 more sources

Simulating transmission of ESKAPE pathogens plus C. difficile in relevant clinical scenarios

BMC Infectious Diseases, 2020
Background The prevalence of healthcare-acquired infections (HAI) and rising levels of antimicrobial resistance places significant economic and public health burdens on modern healthcare systems.
Katharina L. Weber, Danielle S. LeSassier, Anthony D. Kappell, Kathleen Q. Schulte, Nicole Westfall, Nicolette C. Albright, Gene D. Godbold, Veena Palsikar, Carlos A. Acevedo, Krista L. Ternus, F. Curtis Hewitt   +10 more
doaj   +1 more source

Infusion of Some but Not All Types of Human Perinatal Stromal Cells Prevent Organ Fibrosis in a Humanized Graft versus Host Disease Murine Model

Biomedicines, 2023
Allogeneic transplant rejection represents a medical complication that leads to high morbidity and mortality rates. There are no treatments to effectively prevent fibrosis; however, there is great interest in evaluating the use of perinatal mesenchymal ...
Ramon E. Coronado, Elena Stavenschi Toth, Maria Somaraki-Cormier, Naveen Krishnegowda, Shatha Dallo   +4 more
doaj   +1 more source

Plasma-based longitudinal mutation monitoring as a potential predictor of disease progression in subjects with adenocarcinoma in advanced non-small cell lung cancer

BMC Cancer, 2020
Background Identifying and tracking somatic mutations in cell-free DNA (cfDNA) by next-generation sequencing (NGS) has the potential to transform the clinical management of subjects with advanced non-small cell lung cancer (NSCLC). Methods Baseline tumor
John Jiang, Hans-Peter Adams, Maria Lange, Sandra Siemann, Mirjam Feldkamp, Sylvie McNamara, Sebastian Froehler, Stephanie J. Yaung, Lijing Yao, Aarthi Balasubramanyam, Nalin Tikoo, Christine Ju, H. Jost Achenbach, Rainer Krügel, John F. Palma   +14 more
doaj   +1 more source

Case Report: Inhaled Nitroglycerine as an Alternative to Inhaled Nitric Oxide in the Acute Treatment of Pulmonary Hypertension and Impending Acute Right Ventricular Failure in the Intensive Care Unit

European Medical Journal, 2020
In this review, two cases of severe pulmonary hypertension of different classes that have been successfully treated using inhaled nitroglycerine are presented. In a community hospital setting and in cases of life-threatening right heart failure and shock
Khaled Sorour, Christopher Lawson, Omar Sorour, Garrison Davis   +3 more
doaj   +1 more source

Evaluating the Impact of Dropout and Genotyping Error on SNP-Based Kinship Analysis With Forensic Samples

Frontiers in Genetics, 2022
Technological advances in sequencing and single nucleotide polymorphism (SNP) genotyping microarray technology have facilitated advances in forensic analysis beyond short tandem repeat (STR) profiling, enabling the identification of unknown DNA samples ...
Stephen D. Turner, V.P. Nagraj, Matthew Scholz, Shakeel Jessa, Carlos Acevedo, Jianye Ge, Jianye Ge, August E. Woerner, August E. Woerner, Bruce Budowle, Bruce Budowle   +10 more
doaj   +1 more source

Do healthcare needs-based population segments predict outcomes among the elderly? Findings from a prospective cohort study in an urbanized low-income community

BMC Geriatrics, 2020
Background A rapidly ageing population with increasing prevalence of chronic disease presents policymakers the urgent task of tailoring healthcare services to optimally meet changing needs.
Jia Loon Chong, Lian Leng Low, David Bruce Matchar, Rahul Malhotra, Kheng Hock Lee, Julian Thumboo, Angelique Wei-Ming Chan   +6 more
doaj   +1 more source