Results 31 to 40 of about 624,213 (299)

Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase

Cell Reports, 2015
The attenuation of protein synthesis via the phosphorylation of eIF2α is a major stress response of all eukaryotic cells. The growth-arrest- and DNA-damage-induced transcript 34 (GADD34) bound to the serine/threonine protein phosphatase 1 (PP1) is the ...
Meng S. Choy, Permeen Yusoff, Irene C. Lee, Jocelyn C. Newton, Catherine W. Goh, Rebecca Page, Shirish Shenolikar, Wolfgang Peti   +7 more
doaj   +1 more source

Identification and validation of a novel HOX-related classifier signature for predicting prognosis and immune microenvironment in pediatric gliomas

Frontiers in Cell and Developmental Biology, 2023
Background: Pediatric gliomas (PGs) are highly aggressive and predominantly occur in young children. In pediatric gliomas, abnormal expression of Homeobox (HOX) family genes (HFGs) has been observed and is associated with the development and progression ...
Jiao Zhang, Xueguang Zhang, Junyan Su, Jiali Zhang, Siyao Liu, Li Han, Mengyuan Liu, Dawei Sun   +7 more
doaj   +1 more source

Implementation and evaluation of a training program as part of the Cooperative Biological Engagement Program in Azerbaijan

Frontiers in Public Health, 2015
A training program for animal and human health professionals has been implemented in Azerbaijan through a joint agreement between the United States Defense Threat Reduction Agency and the Government of Azerbaijan.
April eJohnson, Gulshan eAkhundova, Saida eAliyeva, Lisa eStrelow   +3 more
doaj   +1 more source

Identification of molecular subtypes based on PANoptosis-related genes and construction of a signature for predicting the prognosis and response to immunotherapy response in hepatocellular carcinoma

Frontiers in Immunology, 2023
BackgroundPrevious studies have demonstrated that PANoptosis is strongly correlated with cancer immunity and progression. This study aimed to develop a PANoptosis-related signature (PANRS) to explore its potential value in predicting the prognosis and ...
Jinfeng Zhu, Qian Huang, Xingyu Peng, Chen Luo, Zitao Liu, Dongdong Liu, Huazhao Yuan, Rongfa Yuan, Xuexin Cheng, Xuexin Cheng, Xuexin Cheng   +10 more
doaj   +1 more source

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small, Pi Chun Cheng, April L. Rahrig, Courtney M. Rowan   +3 more
wiley   +1 more source

An anoikis-related gene signature for prediction of the prognosis in prostate cancer

Frontiers in Oncology, 2023
PurposeThis study presents a novel approach to predict postoperative biochemical recurrence (BCR) in prostate cancer (PCa) patients which involves constructing a signature based on anoikis-related genes (ARGs).MethodsIn this study, we utilised data from ...
Xiaodong Zhao, Xiaodong Zhao, Zuheng Wang, Zuheng Wang, Zilu Tang, Zilu Tang, Jun Hu, Jun Hu, Yulin Zhou, Jingping Ge, Jie Dong, Song Xu, Song Xu   +12 more
doaj   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

The Legal Force of Electronic Signatures in Online Mortgage Registration

Jurnal Penelitian Hukum De Jure, 2021
The legal force of electronic signatures in online mortgage registration activities is an important subject to study. Because basically the legal problems of electronic mortgage registration are also related to the validity of electronic signatures of ...
Zainuddin Zainuddin, Rahmat Ramadhani
doaj   +1 more source

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly   +8 more
wiley   +1 more source

From Pandemic Preparedness to Biofuel Production: Tobacco Finds Its Biotechnology Niche in North America

Agriculture, 2015
In 2012 scientists funded by the United States Defense Advanced Research Projects Agency (DARPA) produced 10 million doses of influenza vaccine in tobacco in a milestone deadline of one month.
Joshua D. Powell
doaj   +1 more source