Results 41 to 50 of about 809,400 (248)

From Languishing Dyslexia to Thriving Dyslexia: Developing a new conceptual approach to working with people with dyslexia

Frontiers in Psychology, 2015
This is an account of personal narratives shared by several people with dyslexia. Most of these are presented in their original quotation format to provide personal accounts of the lives of people with dyslexia.
Chathurika Sewwandi Kannangara
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Generalized Scheme For Fractal Based Digital Signature (GFDS). [PDF]

, 2007
This paper describes a new development in the cryptographic digital signature scheme based on Mandelbrot and Julia fractal sets. Recently it has been shown that it is possible to have digital signature scheme based on fractal due to the strong connection
Alia, Mohammad Ahmad, Samsudin, Azman
core   +1 more source

Automatic segmentation of human cortical layer-complexes and architectural areas using diffusion MRI and its validation

Frontiers in Neuroscience, 2016
Recently, several magnetic resonance imaging contrast mechanisms have been shown to distinguish cortical substructure corresponding to selected cortical layers.
Matteo Bastiani, Matteo Bastiani, Ana-Maria Oros-Peusquens, Arne Seehaus, Daniel Brenner, Klaus Moellenhoff, Avdo Celik, Jörg Felder, Hansjürgen Bratzke, Nadim Jon Shah, Nadim Jon Shah, Ralf Galuske, Rainer Goebel, Rainer Goebel, Alard Roebroeck   +14 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Towards a Learning Mindset: First-Year University Students' Qualitative Perspectives on Gratitude in the Context of Learning Effort

Journal of Student Affairs in Africa, 2021
Signature strengths, such as gratitude, can assist students in navigating the demanding first-year experience. However, more research is needed to explore the role of gratitude in relation to cognitive benefits for students.
Henry Mason
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Develop Your CORE2 for Career Flourishing: A Career Development Workshop for Hospitalists

MedEdPORTAL
Introduction Appreciative inquiry harnesses an individual's strengths to realize positive change, and a flourishing-focused mindset emphasizes engagement, social connectivity, and seeking meaningful work.
Ryan E. Nelson, Emily A. Mallin, Shannon K. Martin   +2 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source