Results 51 to 60 of about 809,400 (248)
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
PLoS ONE, 2020 STRENGTHS AND LIMITATIONS OF THIS STUDY:Our results represent the first comparison of venous and arterial thrombosis at the transcriptomic level.Our main result was the demonstration that immunothrombosis pathways are important to the pathophysiology of ...
Bidossessi Wilfried Hounkpe +3 more
doaj +1 more source
Character strengths in the United Kingdom: the VIA inventory of strengths
, 2007 The development of a classification of strengths, the Values in Action Inventory of Strengths, has done much to advance research into strengths of character. Using an Internet sample of 17,056 UK respondents, we present data on the character strengths of
Seligman, Martin E P +12 more
core +1 more source
Can project managers signature strengths enhance project team resilience, and if so, how? [PDF]
, 2016 Purpose: The purpose of this thesis is to explore the relationship between signature strengths and the development and strengthening of resilience in teams within a project setting. More specifically, this thesis investigates whether project managers can
Kristensen, Anita Hultgren +1 more
core +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Alzheimer’s disease: insights from a network medicine perspective
Scientific Reports, 2022 Alzheimer’s disease (AD) is the most common neurodegenerative disease that currently lacks available effective therapy. Thus, identifying novel molecular biomarkers for diagnosis and treatment of AD is urgently demanded. In this study, we exploited tools
Federica Conte, Paola Paci
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
IET Electric Power Applications, 2022 Flux‐based fault diagnosis methods have attracted ever‐increasing attention from technical communities because of their potential diagnostic capabilities and ability to overcome weaknesses of the traditional methods such as motor current signature ...
Ehsan Mazaheri‐Tehrani, Jawad Faiz
doaj +1 more source