Results 181 to 190 of about 191,753 (296)

Genomic Signatures of Selection Reveal Breed-Specific and Shared Adaptive Regions in South African Beef Cattle. [PDF]

Animals (Basel)
Modiba MC, Magoro AM, Idowu PA, Nephawe KA, Ngcobo JN, Mpofu TJ, Mtileni B.   +6 more
europepmc   +1 more source

A comprehensive water buffalo pangenome reveals extensive structural variation linked to population specific signatures of selection [PDF]

Gigascience
Arshad F, Jayaraman S, Talenti A, Owen R, Mohsin M, Mansoor S, Asif M, Prendergast J.   +7 more
europepmc   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Genomic analysis reveals convergent signatures of selection for milk traits in sheep and goats. [PDF]

J Anim Sci Biotechnol
Akhatayeva Z, Shi Y, Dossybayev K, Malmakov N, Cheng H, Baatar N, Yang J, Li M, Lin K, Xu S.   +9 more
europepmc   +1 more source

Malaria surveillance reveals parasite relatedness, signatures of selection, and correlates of transmission across Senegal. [PDF]

Nat Commun, 2023
Schaffner SF, Badiane A, Khorgade A, Ndiop M, Gomis J, Wong W, Ndiaye YD, Diedhiou Y, Thwing J, Seck MC, Early A, Sy M, Deme A, Diallo MA, Sy N, Sene A, Ndiaye T, Sow D, Dieye B, Ndiaye IM, Gaye A, Ndiaye A, Battle KE, Proctor JL, Bever C, Fall FB, Diallo I, Gaye S, Sene D, Hartl DL, Wirth DF, MacInnis B, Ndiaye D, Volkman SK.   +33 more
europepmc   +1 more source

Selection signatures in sheep

Natural selection pressure favors animals that are better adapted to certain environments. Artificial selection aims to meet the economic needs of animal production. Both affect genetic diversity and can cause genomic modifications in animals.
Rodrigues, Julia Lisboa [UNESP]
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Genomic signatures reveal selection in Lingxian white goose. [PDF]

Poult Sci, 2023
Zheng S, Ouyang J, Liu S, Tang H, Xiong Y, Yan X, Chen H.   +6 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Genomic signatures of selection reveal genetic mechanisms underlying economic traits in Licha black pigs. [PDF]

Anim Biosci
Liu J, Tian Z, Yu M, Li W, Lv P, Wang T, Tian Y, Zhang S, Wang J, Shen W.   +9 more
europepmc   +1 more source