Results 191 to 200 of about 191,753 (296)

Contrasting gene-level signatures of selection with reproductive fitness. [PDF]

Mol Ecol, 2022
Bush SJ, Murren CJ, Urrutia AO, Kover PX.   +3 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Different Paths, Similar Pressures: Divergent Drivers of Genetic Diversity Despite Convergent Genomic Signatures of Selection in Response to Urban Intensity in Two Oligolectic Bee Species. [PDF]

Mol Ecol
Baltz LM, Gardein H, Greil H, Paxton RJ, Theodorou P.   +4 more
europepmc   +1 more source

Genetic diversity and signatures of selection in BoHuai goat revealed by whole-genome sequencing. [PDF]

BMC Genomics, 2023
Yao Z, Zhang S, Wang X, Guo Y, Xin X, Zhang Z, Xu Z, Wang E, Jiang Y, Huang Y.   +9 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Genomic Signatures of Selection Across Climate Gradients and a Geographic Mosaic of Coevolution in an Ant Social Parasite-Host System. [PDF]

Mol Biol Evol
Macit MN, Collin E, Nieto-Blazquez ME, Kever M, Litto M, Jaitner E, Pfenninger M, Feldmeyer B, Foitzik S.   +8 more
europepmc   +1 more source

A genome-wide scan to identify signatures of selection in Lueyang black -bone chicken. [PDF]

Poult Sci, 2023
Xue Z, Wang L, Tian Y, Yang Y, Li P, Yang G, Lu H, Wang S, Zeng W, Zhang T.   +9 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Whole-genome resequencing reveals the genomic diversity and signatures of selection in Romanov sheep. [PDF]

J Anim Sci, 2023
Cao C, Kang Y, Zhou Q, Nanaei HA, Bo D, Liu P, Bai Y, Li R, Jiang Y, Lan X, Pan C.   +10 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source