Results 61 to 70 of about 337,641 (297)
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
The complexity of signed graph and edge-coloured graph homomorphisms
, 2016 We study homomorphism problems of signed graphs from a computational point of view. A signed graph $(G,\Sigma)$ is a graph $G$ where each edge is given a sign, positive or negative; $\Sigma\subseteq E(G)$ denotes the set of negative edges.
Brewster, Richard C. +3 more
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
On signed degrees in signed graphs [PDF]
Czechoslovak Mathematical Journal, 1994 A graph is called signed if there is a designation of its edges as either positive or negative. The signed degree of a vertex \(v\) is the number of positive edges through \(v\) less the number of negative edges through \(v\). The degree sequence consists of signed degrees of all vertices in nonincreasing order.
Chartrand, Gary +3 more
openaire +2 more sources
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Edge-Dual Graph Preserving Sign Prediction for Signed Social Networks
IEEE Access, 2017 Though existing works of sign prediction have reasonable prediction performances, they suffer from the data sparseness problem, especially for the negative link prediction.
Weiwei Yuan +3 more
doaj +1 more source
Homomorphisms of planar signed graphs to signed projective cubes [PDF]
Discrete Mathematics & Theoretical Computer Science, 2013 We conjecture that every signed graph of unbalanced girth 2g, whose underlying graph is bipartite and planar, admits a homomorphism to the signed projective cube of dimension 2g1.
Reza Naserasr +2 more
doaj +1 more source
Discrete Applied MathematicsLet $G$ be a graph and $A$ be its adjacency matrix. A graph $G$ is invertible if its adjacency matrix $A$ is invertible and the inverse of $G$ is a weighted graph with adjacency matrix $A^{-1}$. A signed graph $(G,σ)$ is a weighted graph with a special weight function $σ: E(G)\to \{-1,1\}$. A graph is sign-invertible (or sign-invertible) if its inverse
Isaiah Osborne, Dong Ye
openaire +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
The common minimal dominating signed graph [PDF]
Transactions on Combinatorics, 2012 In this paper, we define the common minimal dominating signedgraph of a given signed graph and offer a structuralcharacterization of common minimal dominating signed graphs. Inthe sequel, we also obtained switching equivalencecharacterizations: $overline{
P. Siva Reddy, B. Prashanth
doaj