Results 101 to 110 of about 41,221 (298)
Consistency in the Naturally Vertex-Signed Line Graph of a Signed Graph [PDF]
Bulletin of the Malaysian Mathematical Sciences Society, 2015 A signed graph is a graph whose edges are signed. In a vertex-signed graph the vertices are signed. The latter is called consistent if the product of signs in every circle is positive. The line graph of a signed graph is naturally vertex-signed. Based on a characterization by Acharya, Acharya, and Sinha in 2009, we give constructions for the signed ...
openaire +3 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
, 2016 [[abstract]]In this paper we introduced a new notion S-antipodal signed graph of a signed graph and its properties are obtained. Also we give the re- lation between antipodal signed graphs and S-antipodal signed graphs.
P. Siva Kota Reddy, B. Prashanth
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Signed Roman Edge k-Domination in Graphs
Discussiones Mathematicae Graph Theory, 2017 Let k ≥ 1 be an integer, and G = (V, E) be a finite and simple graph. The closed neighborhood NG[e] of an edge e in a graph G is the set consisting of e and all edges having a common end-vertex with e.
Asgharsharghi Leila +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Eigenpairs of adjacency matrices of balanced signed graphs
Special MatricesIn this article, we study eigenvalues λ\lambda and their associated eigenvectors xx of the adjacency matrices AA of balanced signed graphs. Balanced signed graphs were first introduced and studied by Harary to handle a problem in social psychology ...
Chen Mei-Qin
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Signed graphs with strong (anti-)reciprocal eigenvalue property
Special MatricesA (signed) graph is said to exhibit the strong reciprocal (anti-reciprocal) eigenvalue property (SR) (resp., (-SR)) if for any eigenvalue λ\lambda , it has 1λ\frac{1}{\lambda } (resp.,−1λ-\frac{1}{\lambda }) as an eigenvalue as well, with the same ...
Belardo Francesco, Huntington Callum
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