Results 81 to 90 of about 252,834 (270)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Eigenpairs of adjacency matrices of balanced signed graphs
Special MatricesIn this article, we study eigenvalues λ\lambda and their associated eigenvectors xx of the adjacency matrices AA of balanced signed graphs. Balanced signed graphs were first introduced and studied by Harary to handle a problem in social psychology ...
Chen Mei-Qin
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Signed graphs with strong (anti-)reciprocal eigenvalue property
Special MatricesA (signed) graph is said to exhibit the strong reciprocal (anti-reciprocal) eigenvalue property (SR) (resp., (-SR)) if for any eigenvalue λ\lambda , it has 1λ\frac{1}{\lambda } (resp.,−1λ-\frac{1}{\lambda }) as an eigenvalue as well, with the same ...
Belardo Francesco, Huntington Callum
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Nonnegative signed total Roman domination in graphs
Communications in Combinatorics and Optimization, 2020 Let $G$ be a finite and simple graph with vertex set $V(G)$. A nonnegative signed total Roman dominating function (NNSTRDF) on a graph $G$ is a function $f:V(G)\rightarrow\{-1, 1, 2\}$ satisfying the conditions that (i) $\sum_{x\in N(v)}f(x)\ge 0$ for
Nasrin Dehgardi, Lutz Volkmann
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Discrete Applied Mathematics, 1980 AbstractA class of signed digraphs which arises naturally, in the theory of sign solvable linear systems is introduced. Several results are obtained concerning the structure of such graphs. Also an application is made revealing much of the structure of matrices of sign-solvable systems.
openaire +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Discrete Applied Mathematics, 2002 A chordally signed graph is defined as a signed chordal graph (each edge is designated as being positive or negative and every induced cycle is a triangle) in which every cycle \(C\) containing an even number of negative edges (positive cycles) has a chord \(e\) such that \(C\cup\{e\}\) forms two positive cycles.
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FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source