Results 81 to 90 of about 41,221 (298)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
On the Powers of Signed Graphs
, 2020 A signed graph is an ordered pair $Σ=(G,σ),$ where $G=(V,E)$ is the underlying graph of $Σ$ with a signature function $σ:E\rightarrow \{1,-1\}$. In this article, we define $n^{th}$ power of a signed graph and discuss some properties of these powers of signed graphs.
T V, Shijin, K A, Germina, K, Shahul
openaire +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Chromatic polynomials of signed graphs
, 2023 Signed graphs are currently enjoying intense interest from the combinatorial community due to various mathematical breakthroughs that relied on results about signed graphs.
Utomo, Charissa Irene
core
Discrete Applied Mathematics, 1980 AbstractA class of signed digraphs which arises naturally, in the theory of sign solvable linear systems is introduced. Several results are obtained concerning the structure of such graphs. Also an application is made revealing much of the structure of matrices of sign-solvable systems.
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On signed degrees in signed graphs [PDF]
Czechoslovak Mathematical Journal, 1994 A graph is called signed if there is a designation of its edges as either positive or negative. The signed degree of a vertex \(v\) is the number of positive edges through \(v\) less the number of negative edges through \(v\). The degree sequence consists of signed degrees of all vertices in nonincreasing order.
Chartrand, Gary +3 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The Chromatic Number of a Signed Graph [PDF]
The Electronic Journal of Combinatorics, 2016 In 1982, Zaslavsky introduced the concept of a proper vertex colouring of a signed graph $G$ as a mapping $\phi\colon V(G)\to \mathbb{Z}$ such that for any two adjacent vertices $u$ and $v$ the colour $\phi(u)$ is different from the colour $\sigma(uv)\phi(v)$, where is $\sigma(uv)$ is the sign of the edge $uv$.
Edita Mácajová +2 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
On net-Laplacian energy of signed graphs
Communications in Combinatorics and Optimization, 2017 A signed graph is a graph where the edges are assigned either positive or negative signs. Net degree of a signed graph is the difference between the number of positive and negative edges incident with a vertex. It is said to be net-regular if all its
Nutan G. Nayak
doaj +1 more source