Results 81 to 90 of about 39,748 (262)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Eigenpairs of adjacency matrices of balanced signed graphs
Special MatricesIn this article, we study eigenvalues λ\lambda and their associated eigenvectors xx of the adjacency matrices AA of balanced signed graphs. Balanced signed graphs were first introduced and studied by Harary to handle a problem in social psychology ...
Chen Mei-Qin
doaj +1 more source
Discrete Applied Mathematics, 2002 A chordally signed graph is defined as a signed chordal graph (each edge is designated as being positive or negative and every induced cycle is a triangle) in which every cycle \(C\) containing an even number of negative edges (positive cycles) has a chord \(e\) such that \(C\cup\{e\}\) forms two positive cycles.
openaire +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Signed graphs with strong (anti-)reciprocal eigenvalue property
Special MatricesA (signed) graph is said to exhibit the strong reciprocal (anti-reciprocal) eigenvalue property (SR) (resp., (-SR)) if for any eigenvalue λ\lambda , it has 1λ\frac{1}{\lambda } (resp.,−1λ-\frac{1}{\lambda }) as an eigenvalue as well, with the same ...
Belardo Francesco, Huntington Callum
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Nonnegative signed total Roman domination in graphs
Communications in Combinatorics and Optimization, 2020 Let $G$ be a finite and simple graph with vertex set $V(G)$. A nonnegative signed total Roman dominating function (NNSTRDF) on a graph $G$ is a function $f:V(G)\rightarrow\{-1, 1, 2\}$ satisfying the conditions that (i) $\sum_{x\in N(v)}f(x)\ge 0$ for
Nasrin Dehgardi, Lutz Volkmann
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ICASSP 2026 - 2026 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)The proliferation of signed networks in contemporary social media platforms necessitates robust privacy-preserving mechanisms. Graph unlearning, which aims to eliminate the influence of specific data points from trained models without full retraining, becomes particularly critical in these scenarios where user interactions are sensitive and dynamic ...
Zhifei Luo +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source