Results 61 to 70 of about 735,632 (298)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Estrada Index and Some Properties of Partially Signed Graphs [PDF]
Mathematics Interdisciplinary ResearchA signed graph is a graph with signed edges. Recently, a special graph consisting of signed and unsigned edges has been introduced and is called a partially signed graph.
Shila Razavi, Gholam Fath-Tabar
doaj +1 more source
Star complements for ±2 in signed graphs
Special Matrices, 2022 In this article, we investigate connected signed graphs which have a connected star complement for both −2-2 and 2 (i.e. simultaneously for the two eigenvalues), where −2-2 (resp.
Mulas Raffaella, Stanić Zoran
doaj +1 more source
Signed graphs with integral net Laplacian spectrum
AKCE International Journal of Graphs and Combinatorics, 2023 Given a signed graph [Formula: see text], let [Formula: see text] and [Formula: see text] be its standard adjacency matrix and the diagonal matrix of net-degrees, respectively.
M. Anđelić +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Bipartite Consensus Problems on Second-Order Signed Networks With Heterogeneous Topologies
IEEE Access, 2020 This paper is devoted to the convergence problem for second-order signed networks that are associated with two signed graphs in the presence of heterogeneous topologies.
Jianheng Ling +2 more
doaj +1 more source
Discrete Applied Mathematics, 1981 AbstractA signed graph based on F is an ordinary graph F with each edge marked as positive or negative. Such a graph is called balanced if each of its cycles includes an even number of negative edges. Psychologists are sometimes interested in the smallest number d=d(G) such that a signed graph G may be converted into a balanced graph by changing the ...
Jin Akiyama +3 more
openaire +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source