Results 51 to 60 of about 252,834 (270)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Bipartite Consensus Problems on Second-Order Signed Networks With Heterogeneous Topologies
IEEE Access, 2020 This paper is devoted to the convergence problem for second-order signed networks that are associated with two signed graphs in the presence of heterogeneous topologies.
Jianheng Ling +2 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Signed Complete Graphs with Maximum Index
Discussiones Mathematicae Graph Theory, 2020 Let Γ = (G, σ) be a signed graph, where G is the underlying simple graph and σ E(G) → {−, +} is the sign function on the edges of G. The adjacency matrix of a signed graph has −1 or +1 for adjacent vertices, depending on the sign of the edges.
Akbari Saieed +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Signed graphs with integral net Laplacian spectrum
AKCE International Journal of Graphs and Combinatorics, 2023 Given a signed graph [Formula: see text], let [Formula: see text] and [Formula: see text] be its standard adjacency matrix and the diagonal matrix of net-degrees, respectively.
M. Anđelić +3 more
doaj +1 more source
On signed degrees in signed graphs [PDF]
Czechoslovak Mathematical Journal, 1994 A graph is called signed if there is a designation of its edges as either positive or negative. The signed degree of a vertex \(v\) is the number of positive edges through \(v\) less the number of negative edges through \(v\). The degree sequence consists of signed degrees of all vertices in nonincreasing order.
Chartrand, Gary +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Discrete Applied MathematicsLet $G$ be a graph and $A$ be its adjacency matrix. A graph $G$ is invertible if its adjacency matrix $A$ is invertible and the inverse of $G$ is a weighted graph with adjacency matrix $A^{-1}$. A signed graph $(G,σ)$ is a weighted graph with a special weight function $σ: E(G)\to \{-1,1\}$. A graph is sign-invertible (or sign-invertible) if its inverse
Isaiah Osborne, Dong Ye
openaire +2 more sources