Results 71 to 80 of about 252,834 (270)
Whole-Graph Representation Learning for the Classification of Signed Networks
IEEE AccessGraphs are ubiquitous for modeling complex systems involving structured data and relationships. Consequently, graph representation learning, which aims to automatically learn low-dimensional representations of graphs, has drawn a lot of attention in ...
Noe Cecillon +3 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Discussiones Mathematicae Graph Theory, 2015 A signed graph (or sigraph for short) is an ordered pair S = (Su,σ), where Su is a graph, G = (V,E), called the underlying graph of S and σ : E → {+,−} is a function from the edge set E of Su into the set {+,−}.
Sinha Deepa, Dhama Ayushi
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Signed graphs connected with the root lattice
Bibechana, 2014 For any base of the root lattice (An) we can construct a signed graph. A signed graph is one whose edges are signed by +1 or -1. A signed graph is balanced if and only if its vertex set can be divided into two sets-either of which may be empty–so that ...
RN Yadav
doaj +3 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Signed Roman Edge k-Domination in Graphs
Discussiones Mathematicae Graph Theory, 2017 Let k ≥ 1 be an integer, and G = (V, E) be a finite and simple graph. The closed neighborhood NG[e] of an edge e in a graph G is the set consisting of e and all edges having a common end-vertex with e.
Asgharsharghi Leila +2 more
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Signed graphs, regular matroids, grafts [PDF]
Mathematics
Gerards, A.M.H., Schrijver, A.
core +1 more source