Results 91 to 100 of about 41,221 (298)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Whole-Graph Representation Learning for the Classification of Signed Networks

open access: yesIEEE Access
Graphs are ubiquitous for modeling complex systems involving structured data and relationships. Consequently, graph representation learning, which aims to automatically learn low-dimensional representations of graphs, has drawn a lot of attention in ...
Noe Cecillon   +3 more
doaj   +1 more source

Chromatic invariants of signed graphs

open access: yes, 1982
We continue the study initiated in “Signed graph coloring” of the chromatic and Whitney polynomials of signed graphs. In this article we prove and apply to examples three types of general theorem which have no analogs for ordinary graph coloring.
Zaslavsky, Thomas
core   +1 more source

Signed graph coloring

open access: yesDiscrete Mathematics, 1982
AbstractColoring a signed graph by signed colors, one has a chromatic polynomial with the same enumerative and algebraic properties as for ordinary graphs. New phenomena are the interpretability only of odd arguments and the existence of a second chromatic polynomial counting zero-free colorings. The generalization to voltage graphs is outlined.
openaire   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

On •-Line Signed Graphs L•(S)

open access: yesDiscussiones Mathematicae Graph Theory, 2015
A signed graph (or sigraph for short) is an ordered pair S = (Su,σ), where Su is a graph, G = (V,E), called the underlying graph of S and σ : E → {+,−} is a function from the edge set E of Su into the set {+,−}.
Sinha Deepa, Dhama Ayushi
doaj   +1 more source

Signed Graph Convolutional Networks

open access: yes2018 IEEE International Conference on Data Mining (ICDM), 2018
Due to the fact much of today's data can be represented as graphs, there has been a demand for generalizing neural network models for graph data. One recent direction that has shown fruitful results, and therefore growing interest, is the usage of graph convolutional neural networks (GCNs). They have been shown to provide a significant improvement on a
Tyler Derr, Yao Ma 0001, Jiliang Tang
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Signed graphs connected with the root lattice

open access: yesBibechana, 2014
For any base of the root lattice (An) we can construct a signed graph. A signed graph is one whose edges are signed by +1 or -1. A signed graph is balanced if and only if its vertex set can be divided into two sets-either of which may be empty–so that ...
RN Yadav
doaj   +3 more sources

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