Results 41 to 50 of about 146,402 (261)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Degree of an edge and Platt Number in signed networks
Ratio Mathematica, 2023 Positive labelled edges play a vital role in network analysis.The degree of edges in signed graphs is introduced by giving importance to positive edges incident on the end vertices of that edge. The concept of Platt number of a graph, which is the sum of
Diviya K D, Anjaly Kishore
doaj +1 more source
Signed Graph Attention Networks [PDF]
, 2019 Accepted and to appear at ...
Junjie Huang +3 more
openaire +4 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Connectivity and Reachability in Signed Networks [PDF]
J. Univers. Comput. Sci., 2007 JUCS - Journal of Universal Computer Science Volume Nr.
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Stability of phase-locked states in signed Kuramoto networks: structure versus adaptation
Journal of Physics: ComplexityAdaptive Kuramoto models admit a variety of nontrivial phase-locked configurations, including antipodal and rotating-wave states. A central open question is whether the observed persistence of such configurations can be attributed to intrinsic properties
Jaeyoung Yoon, Christian Kuehn
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A technique of algorithms construction for solving a correlation clustering problem
Discrete and Continuous Models and Applied Computational ScienceWe propose a construction method for network structure based algorithms (NS-algorithms), aimed at solving the correlation clustering problem (CCP) specifically for signed networks. Our model assumes an undirected, unweighted simple signed graph.
Ellada I. Ibragimova +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source