Results 51 to 60 of about 146,402 (261)

SNE: Signed Network Embedding [PDF]

open access: yes, 2017
Several network embedding models have been developed for unsigned networks. However, these models based on skip-gram cannot be applied to signed networks because they can only deal with one type of link. In this paper, we present our signed network embedding model called SNE. Our SNE adopts the log-bilinear model, uses node representations of all nodes
Shuhan Yuan, Xintao Wu, Yang Xiang 0006
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Opinion dynamics with intermittent‐influence leaders on the signed social network

open access: yesEngineering Reports, 2023
In this paper, the leader‐follower architecture is constructed by combining intermittent‐influence leaders with a signed social network. Unlike a typical network with leaders where leaders are supposed to continuously influence followers, in this article,
Ziwen Shen   +4 more
doaj   +1 more source

Link-Sign Prediction in Dynamic Signed Directed Networks [PDF]

open access: yes2018 IEEE 4th International Conference on Collaboration and Internet Computing (CIC), 2018
Many real-world applications can be modeled as signed directed graphs wherein the links between nodes can have either positive or negative signs. Social networks can be modeled as signed directed graphs where positive/negative links represent trust/distrust relationships between users.In order to predict user behavior in social networks, several ...
Dang, Quang-Vinh, Ignat, Claudia-Lavinia
openaire   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Evolutionary Model of Signed Edges in Online Networks Based on Infinite One-Dimensional Uniform Lattice

open access: yesMathematics
The aim of this paper is to study the evolutionary dynamic model for signed edges as observed in online signed social networks. We introduce the incremental mechanism of signed edges behind a simple random walk and explain how this relates to Brownian ...
Zhenpeng Li, Zhihua Yan, Xijin Tang
doaj   +1 more source

DSSAM: digitally signed secure acknowledgement method for mobile ad hoc network

open access: yesEURASIP Journal on Wireless Communications and Networking, 2021
Mobile ad hoc network (MANET) is an infrastructure-less, self-motivated, arbitrary, self-configuring, rapidly changing, multi-hop network that is self-possessing wireless bandwidth-conscious links without centrally managed router support.
Ashutosh Srivastava   +5 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy