Results 91 to 100 of about 1,312,146 (265)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

SIGNIFICANT LEARNING IN VIRTUAL LEARNING ENVIRONMENTS

, 2016
Este artículo tiene el objetivo de hacer una relación de perspectivas de diversos estudios referentes a Educación a Distancia y sus Ambientes Virtuales de Aprendizaje (AVA) frente un Aprendizaje Significativo. En este sentido, este texto tiene la intención de hacer una lista de aspectos importantes de esta herramienta en el proceso de enseñanza y ...
Rolim, Anderson Teixeira, Scaramuzza, Bruno Cézar   +1 more
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

AS RELAÇÕES ENTRE APRENDIZAGEM SIGNIFICATIVA E REPRESENTAÇÕES MULTIMODAIS

Ensaio Pesquisa em Educação em Ciências
A linha de pesquisa em multimodos de representações vem atualmente sendo destacada como instrumento de instrução na educação científica. Partindo dos fundamentos que justificam um encaminhamento didático à luz dos multimodos de representações, este ...
Andreia de Freitas Zompero, Carlos Eduardo Laburú   +1 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Jurist formation: developing teaching and significant learning

Revista MENDIVE, 2015
With the present study, we aim to approach the learning pr ocess of the future lawyer, focusing on Criminal Law as a specific Discipline in the Law major.
Liyanis Santana Santana, Julio Llanes Robaina, Ulises David Zubizarreta   +2 more
doaj  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Corrosion and significant learning of redox

, 2021
La oxi-reducción puede ser considerada en la enseñanza de la química como un contenido difícil de trabajar y asimilar por docentes y estudiantes, por su carácter abstracto y el lenguaje utilizado, destacando la necesidad de acciones que faciliten la asimilación de conceptos y consideren el conocimiento previo de los estudiantes con el fin de facilitar ...
Gomes, Duliane da Costa, Souza, Katiuscia dos Santos de   +1 more
openaire   +1 more source