Results 91 to 100 of about 35,832 (220)

The issue of recreational use of sildenafil

Journal of Education, Health and Sport
Introduction and purpose Erectile dysfunction (ED) is defined as the inability to achieve and maintain an erection sufficient for satisfactory sexual intercourse.
Krystian Wdowiak, Agnieszka Maciocha, Julia Wąż, Aleksandra Witas, Justyna Drogoń, Weronika Chachaj, Paulina Słomka, Edyta Gwóźdź, Dawid Konieczko, Ewa Gardocka   +9 more
doaj   +1 more source

The Silver Jubilee (2025) of Insulin Glargine: Introducing the Era of Long‐Acting Insulin Analogues for Diabetes Mellitus

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5527-5541, July 2026.
ABSTRACT In the year 2000 the first once daily long‐acting bioengineered insulin analogue (LAIA), insulin glargine (‘glargine’), a true basal insulin (BI), became available for clinical use. This led to the decline in the 50‐year‐old era and prominence of the intermediate‐acting insulins, neutral protamine Hagedorn (NPH) and lente, requiring twice ...
Geremia B. Bolli, Philip D. Home, Mauro Lepore, Matthew C. Riddle, Francesca Porcellati, Carmine G. Fanelli, Paola Lucidi, Hannele Yki‐Järvinen, Reinhard H. Becker, David R. Owens   +9 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Trametinib Therapy for Hypertrophic Cardiomyopathy and Pulmonary Hypertension in a Child With RAF1‐Related Noonan Syndrome (p.Ser257Leu): A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT This case describes a female infant with RAF1‐related Noonan syndrome who developed severe hypertrophic obstructive cardiomyopathy, pulmonary hypertension, and cardiorespiratory failure that responded to trametinib treatment but ultimately progressed to death following dose tapering and discontinuation of therapy. To the best of our knowledge,
C. Noah Nilsson, Othman A. Aljohani, Michael A. Smith, Rachelle Durand, Inger Norlyk Sheyanth, Hythem Nawaytou, Elliot Stieglitz, Russel Valle, Sanjeev A. Datar   +8 more
wiley   +1 more source

The Supporting Role of Natural Products as Effective Adjuvants in Cancer Immunotherapy

eFood, Volume 7, Issue 3, June 2026.
Natural products, as multi‐target and low‐toxicity adjuvants, enhance immune checkpoint inhibitor responses and reduce immune‐related adverse events through T cell reprogramming, microenvironment remodeling, and microbiota‐immune modulation. ABSTRACT Immune checkpoint inhibitors (ICIs) have revolutionized the treatment landscape of malignant tumors ...
Boyang Liu, Yubin Huang, Jianjun Deng, Zhijun Mao, Xue Bai, Longyang Ma, Jianhua Wang   +6 more
wiley   +1 more source

Application of Sandpaper Spray Mass Spectrometry (SPS‐MS) for the Recognition of Sweeteners in Candies and Gums

Journal of Mass Spectrometry, Volume 61, Issue 6, June 2026.
ABSTRACT The detection of sweeteners in complex food matrices remains analytically challenging. The present study evaluates sandpaper spray mass spectrometry (SPS‐MS) as a rapid, direct, no‐sample‐preparation screening approach for sugar‐free candies and chewing gums.
Sarah Fernandes Coelho Viana, Adriana Nori de Macedo, Rodinei Augusti   +2 more
wiley   +1 more source

Effects of pioglitazone on erectile dysfunction in sildenafil poor-responders: a randomized, controlled study

Journal of Pharmacy & Pharmaceutical Sciences, 2008
Purpose.To assess the effects of pioglitazone on sildenafil responsiveness in men with erectile dysfunction (ED) and a history of poor response to sildenafil. Methods. In a double -blinded study, 38 men aged 47 ± 1.5 years with moderate-to-severe ED and
Babak Gholamine, Manijeh Motevallian, Massoumeh Shafiei, Massoud Mahmoudian   +3 more
doaj   +1 more source

Swimming-Induced Pulmonary Edema: Pathophysiology and Risk Reduction With Sildenafil

Circulation, 2016
Background Swimming-induced pulmonary edema (SIPE) occurs during swimming or scuba diving, often in young individuals with no predisposing conditions, and its pathophysiology is poorly understood.
R. Moon, Stefanie D. Martina, D. Peacher, Jennifer V F Potter, T. Wester, A. D. Cherry, M. Natoli, C. Otteni, D. Kernagis, W. D. White, J. Freiberger   +10 more
semanticscholar   +1 more source

Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?

Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley   +1 more source

Advances in Erectile Dysfunction Management: What Does Work

Trends in Urology &Men's Health, Volume 17, Issue 3, June 2026.
ABSTRACT Erectile dysfunction (ED) is a prevalent and multifactorial disorder that substantially affects quality of life. Pathophysiology includes vascular, neurogenic, drug‐induced, and psychogenic causes, and frequently coexists with cardiometabolic disease.
Jolie Shen, Daye Park, Jasper Bash, Juan Andino   +3 more
wiley   +1 more source