Results 71 to 80 of about 19,757 (182)
Journal of Pharmacy & Pharmaceutical Sciences, 2008 Purpose.To assess the effects of pioglitazone on sildenafil responsiveness in men with erectile dysfunction (ED) and a history of poor response to sildenafil. Methods. In a double -blinded study, 38 men aged 47 ± 1.5 years with moderate-to-severe ED and
Babak Gholamine +3 more
doaj +1 more source
Transfusion Medicine, EarlyView.Abstract Objectives To assess the impact of the individualised risk‐based donor selection guidelines on deferral of blood donors at donation sessions in England. Background From June 2021, the 3‐month deferral for sex between men was replaced by an individualised risk assessment known as FAIR (For the Assessment of Individualised Risk).
Katherine Daly +3 more
wiley +1 more source
What Causes Geographic Variation in Drug Prescribing? Evidence from Physician Migration
The RAND Journal of Economics, Volume 57, Issue 3, Page 601-626, Autumn (Fall) 2026.ABSTRACT In this article, we examine the importance of individual physicians in explaining the significant variation in prescription drug spending in Medicare Part D. By tracking prescribing behavior before and after physician relocations, we find that movers' prescribing converges toward the average of their new location.
David Beheshti, Seth Neller
wiley +1 more source
Andrology, Volume 14, Issue 6, Page 1684-1700, September 2026.ABSTRACT Introduction Erectile dysfunction (ED) significantly impacts quality of life. For patients unresponsive to conservative treatments, penile prosthesis implantation represents an effective solution with high satisfaction rates. However, the complexity and sensitive nature of the procedure often generate multiple patient concerns.
Gabriele Tulone +7 more
wiley +1 more source
Vitamin B3 (Nicotinamide) Supplementation in Primary and Scleroderma‐Related Raynaud Phenomenon
ACR Open Rheumatology, Volume 8, Issue 8, August 2026.Objective The aim of this study was to explore if vitamin B3 (nicotinamide) supplementation is a safe and effective adjunctive therapy for patients with primary Raynaud phenomenon (RP) and scleroderma‐related RP. The effect of nicotinamide supplementation in human patients with RP has not been studied before.
Mogeshni Govender +8 more
wiley +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2723-2740, August 2026.Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga +20 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT A 15‐year‐old postpartum primipara presented at 19 days with aphasia, right hemiparesis, chest pain, and dyspnea. Diagnostics confirmed concurrent cardioembolic stroke and pulmonary embolism secondary to peripartum cardiomyopathy (ejection fraction 29%).
Reuben E. Mkama +39 more
wiley +1 more source
SIRT Family: Biological Functions and Therapeutic Targets
MedComm, Volume 7, Issue 8, August 2026.SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang +9 more
wiley +1 more source
Hypotensive Episodes Precede Cognitive Fluctuations in Parkinson's Disease Dementia
Movement Disorders Clinical Practice, Volume 13, Issue 8, Page 1967-1971, August 2026.Abstract Background Cognitive fluctuations (CFs) are a disabling feature in Parkinson's disease dementia (PDD) and contribute to caregiver burden. The relationship between CFs and neurogenic orthostatic hypotension (nOH), a common autonomic complication in PDD, has not been adequately examined.
Jorge Patino +6 more
wiley +1 more source
Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.ABSTRACT Interindividual variability (IIV) in drug response complicates both fixed‐dose design and individualized therapy. Understanding how pharmacokinetic (PK) and pharmacodynamic (PD) processes jointly shape this variability is essential, particularly in combination therapy, where multiple interacting pathways influence outcomes. This study employed
Kuteesa R. Bisaso +3 more
wiley +1 more source