Results 81 to 90 of about 19,757 (182)

Using Pharmacovigilance Data for Signal Detection of Drug Interactions for Rosuvastatin

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
ABSTRACT The 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase inhibitor rosuvastatin is a substrate of breast cancer resistance protein (BCRP). BCRP inhibition increases rosuvastatin plasma concentrations and may result in concentration‐dependent muscle toxicity, at worst rhabdomyolysis.
Ronja Levomäki, Päivi Hirvensalo, Aleksi Tornio, Anne M. Filppula   +3 more
wiley   +1 more source

Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?

Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley   +1 more source

The Evolving Landscape of Pulmonary Hypertension Treatment: From Vasodilation to Disease Modification

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Pulmonary hypertension (PH) is a complex disorder associated with significant morbidity and mortality. PH is characterized by an elevated pulmonary vascular load, leading to right ventricular dysfunction and remodeling, with right heart failure and premature death if left untreated.
Surya Ayalasomayajula, Ednan K. Bajwa, Alexandra G. Cornell, Maria Jose Loureiro, Samuel S. Kim, Julia Richmond DiBello, Eric Sterner, Richard Chen, Islam R. Younis   +8 more
wiley   +1 more source

The Survey of Angiogenesis and Myometrial Thickness of Preimplantation Mouse Uterine in Natural Cycle in those Received Human Menopausal Gonadotropin-Human Chorionic Gonadotropin (HMG–HCG) and Sildenafil Citrate

مجله دانشکده پزشکی اصفهان, 2017
Background: Uterus myometrium contractions play crucial role in break or successful embryo implantation. Furthermore, efficient myometrial angiogenesis is important event for supplying endometrium blood.
Gholamreza Dashti, Ariubarzan Farhadi, Mohammad Javad Saeedi-Borujeni, Bahman Rashidi   +3 more
doaj  

Sildenafil effect on testosterone-induced prostate hypertrophy and relaxation of urinary bladder neck muscles

Toxicology Reports
Background: Previous studies have demonstrated the expression of phosphodiesterase-5 receptors in prostate tissue. In this study, we investigated the efficacy of sildenafil citrate in testosterone-induced benign prostate hyperplasia (BPH) in rabbits ...
Qasim A. El-Dwairi, Karem H. Alzoubi, Rania Mahafdeh   +2 more
doaj   +1 more source

Sildenafil potentiates the antitumor activity of cisplatin by induction of apoptosis and inhibition of proliferation and angiogenesis

Drug Design, Development and Therapy, 2016
Mona Mohamed El-Naa,1 Mohamed Othman,2,3 Sheren Younes4,5 1Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), 6 October City, Egypt; 2Preparatory Year College, University of Hail, Hail, Kingdom of Saudi Arabia; 3Faculty of ...
El-Naa MM, Othman M, Younes S
doaj  

Safety of Sildenafil in Premature Infants with Severe Bronchopulmonary Dysplasia (SILDI-SAFE): A Randomized Controlled Trial. [PDF]

J Pediatr
Jackson WM, Foote HP, Stephenson N, Kemp SM, Moore RT, Nitkin CR, Stewart D, Pryhuber GS, Berger JT, Shukla A, England A, Ford SM, Parton LA, Check JF, Hanna MH, Lagoski M, Krishnan R, Leeman KT, Vyas-Read S, Hudak ML, Katheria AC, Pillers DM, Ji J, Banfro F, Nelin LD, McCulloch M, Ahmad K, Laughon MM, Hornik CP, SILDI-SAFE Study Group.   +29 more
europepmc   +1 more source

Effect of sildenafil on platelet activation and mediators of vascular remodelling during LVAD support. [PDF]

ESC Heart Fail
Saeed O, Patel SR, Farooq M, Reyes Gil M, Solorzano C, Afrifa F, Xue X, Ramos JO, Vukelic S, Madan S, Rochlani Y, Murthy S, Sims DB, Shin J, Goldstein DJ, Sibinga N, Yazdanbakhsh K, Kizer JR, Jorde UP.   +18 more
europepmc   +1 more source

Proarrhythmic Risk Assessment of Sildenafil under High-Dose Misuse Conditions Using the Comprehensive In Vitro Proarrhythmia Assay (CiPA). [PDF]

Biomol Ther (Seoul)
Kim H, Na TW, Jung I, Kang M, Park S, Kwon CH, Jung K.   +6 more
europepmc   +1 more source

Pulmonary vasodilator therapy in COPD-associated pulmonary hypertension: A real-world case series of 14 patients confirmed by right heart catheterization. [PDF]

Respir Med Case Rep
Vera Ricaurte M, Kosak Lopez E, Geller A, Leguizamon R, Lam J, Srikulmontri T, Helena Siqueira Tavares de Melo M, Stavola T, Malin J, Martinez-Manzano JM, Pacheco E.   +10 more
europepmc   +1 more source