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Effects of Sildenafil Citrate on Defibrillation Efficacy

Journal of Cardiovascular Electrophysiology, 2006
Introduction: Although fatal arrhythmia and sudden death have been reported in patients taking sildenafil citrate, its effect on defibrillation efficacy has not been investigated. The aim of this study was to test the hypothesis that sildenafil citrate increases the shock strength required to successfully defibrillate during ventricular fibrillation ...
Krekwit, Shinlapawittayatorn   +3 more
openaire   +2 more sources

Sildenafil citrate for the treatment of pulmonary hypertension

Drugs of Today, 2006
Pulmonary arterial hypertension is a progressive disease that has a high rate of mortality. For these reasons, early treatment is essential. Treatment choices for pulmonary arterial hypertension are limited by drug tolerability, drug cost and inconvenience associated with administration techniques and dosing schedules.
Sandra L, Hrometz, Kelly M, Shields
openaire   +2 more sources

Effects of sildenafil citrate on human hemodynamics

The American Journal of Cardiology, 1999
Nitric oxide (NO) induces the formation of intracellular cyclic guanosine monophosphate (cGMP) by guanylate cyclase. Sildenafil, which selectively inhibits phosphodiesterase type 5 (PDE5) found predominantly in the corpora cavernosa of the penis, effectively blocks the degradation of cGMP and enhances erectile function in men with erectile dysfunction.
G, Jackson   +3 more
openaire   +2 more sources

Effect of Sildenafil Citrate on Postprandial Gallbladder Motility

Southern Medical Journal, 2006
Sildenafil stimulates the nitric oxide-cyclic guanosine monophosphate (NO-cGMP) pathway through inhibition of type 5 phosphodiesterase. NO-cGMP pathway causes smooth muscle relaxation. The aim of this study is to evaluate the effects of sildenafil on gallbladder motility.Twenty healthy male volunteers (21-35 years old) participated in this randomized ...
Degirmenci, Bumin   +6 more
openaire   +3 more sources

Sildenafil citrate.

Journal of the Indian Medical Association, 2001
A BADWAN   +4 more
  +5 more sources

Sildenafil Citrate Ingestion in a Pediatric Patient

Pediatric Emergency Care, 2004
Sildenafil citrate is the first FDA-approved oral agent for male erectile dysfunction. Common adverse effects include flushing, headache, and dyspepsia, although more serious side effects have been reported. Because of its specific therapeutic indication, sildenafil toxicity has been limited almost exclusively to adults. We report a symptomatic case of
openaire   +2 more sources

Sildenafil Citrate Therapy for Oligohydramnios

Obstetrics & Gynecology, 2017
OBJECTIVE: To compare sildenafil plus hydration with hydration alone in improving the amniotic fluid index and neonatal outcomes in pregnancies complicated by idiopathic oligohydramnios ( amniotic fluid index less than 5 cm without underlying maternal or fetal causes and with normal fetal growth).
Mohammad Ahmed, Maher   +2 more
openaire   +2 more sources

Pharmacology of sildenafil citrate.

Indian journal of physiology and pharmacology, 1999
Erectile dysfunction is a common and multi-factorial disease that strongly impairs the quality of life in men. During the past decade, many new therapeutic strategies have become available. But the need for oral treatment was strongly felt. This need appears to have been fulfilled with the introduction of sildenafil.
D N, Umrani, R K, Goyal
openaire   +1 more source

FIA of sildenafil citrate using UV-detection

Journal of Pharmaceutical and Biomedical Analysis, 2001
A flow injection analysis (FIA) of sildenafil citrate (SLD) using UV detection is described in this study. The best solvent system was found to be consisting of 0.2 M phosphate buffer at pH 8 having 10% MeOH. A flow rate of 1 ml. min(-1) was pumped and active material was detected at 292 nm.
Altıokka, Göksel   +3 more
openaire   +2 more sources

Effects of Testosterone Replacement on Response to Sildenafil Citrate

Annals of Internal Medicine, 2013
Comment in In response. Effects of testosterone replacement on response to sildenafil citrate. [Ann Intern Med. 2013] In response. Effects of testosterone replacement on response to sildenafil citrate.Spitzer M, Basaria S, Travison TG, Bhasin S. Ann Intern Med. 2013 Apr 2; 158(7):570-1.
Aversa A   +3 more
openaire   +4 more sources

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