Results 81 to 90 of about 9,248 (216)

EFFECT OF SILDENAFIL CITRATE ON THE BODY WEIGHT, BLOOD GLUCOSE AND WHITE BLOOD CELL COUNT DURING WOUND HEALING PROCESS IN DIABETIC RATS [PDF]

open access: yesKanem Journal of Medical Sciences, 2016
Background: Diabetes mellitus is a chronic metabolic disorder with major complication of delayed wound healing. Objectives: The purpose of this study was to evaluate the effect of sildenafil on blood glucose level, body weight and leucocyte count during ...
Ngulde SI   +8 more
doaj  

A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]

open access: yes, 2012
Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
core   +2 more sources

Vitamin D deficiency induces erectile dysfunction: Role of superoxide and Slpi

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 15, Page 3669-3687, August 2025.
Background and Purpose Epidemiological studies suggest a relationship between vitamin D deficiency and erectile dysfunction (ED). We hypothesized that vitamin D deficiency or vitamin D receptor (VDR) knockout causes ED and analysed the underlying molecular mechanisms.
Miguel A. Olivencia   +14 more
wiley   +1 more source

Xanthine Derivative KMUP‐3 Alleviates Periodontal Bone Resorption by Inhibiting Osteoclastogenesis and Macrophage Pyroptosis

open access: yesJournal of Periodontal Research, Volume 60, Issue 7, Page 723-736, July 2025.
This study reveals that our self‐developed xanthine derivative, KMUP‐3, suppresses osteoclastogenesis, inflammation, and pyroptosis by inhibiting the NLRP3 inflammasome. It also alleviates periodontal bone loss in periodontitis rats, highlighting its potential as a novel therapeutic option for periodontitis.
Shang‐En Huang   +7 more
wiley   +1 more source

Comparison of the effect of Elaeagnus angustifolia flower capsule and sildenafil citrate tablet female sexual interest/arousal disorder in clinical trial study

open access: yesJournal of Family Medicine and Primary Care, 2019
Background and Aims: Sexual desire is one of the main issues affecting people's individual and social life. The present study aimed to compare the effects of Elaeagnus angustifolia extract and sildenafil citrate tablet on female sexual interest/arousal ...
Sanaz Zeinalzadeh   +3 more
doaj   +1 more source

Sildenafil as a therapeutic option for digital ischemic ulceration: case report. [PDF]

open access: yes, 2015
We report the case of a 37-year-old woman who developed critical upper limb ischemia caused by a cervical rib. Because the malformation was initially undiagnosed, a vascular bypass was performed, and failure occurred.
Applegate, L.A.   +5 more
core   +1 more source

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

open access: yesAdvanced Materials Interfaces, Volume 12, Issue 11, June 9, 2025.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui   +5 more
wiley   +1 more source

EXPERIMENTAL STUDY: THE EFFICACY AND DOSAGE OF SILDENAFIL CITRATE ON FLAP VIABILITY

open access: yesUrology Research and Practice, 2019
Introduction: Various agents have been studied to observe the effects on flap viability, necrosis and the wound healing. Sildenafil citrate is a phospodiesterase type 5 enzyme inhibitor, which increases cGMP levels, is used generally in the treatment of ...
Ali Ayyıldız   +5 more
doaj   +2 more sources

Валидация методики определения силденафила цитрата в плазме крови кроликов [PDF]

open access: yes, 2019
СИЛДЕНАФИЛПЛАЗМАКРОВИ ПЛАЗМАЛЕКАРСТВ ОЦЕНКА ДОКЛИНИЧЕСКАЯ /МЕТОДЫЛЕКАРСТВЕННЫЙ СКРИНИНГ /МЕТОДЫОЦЕНОЧНЫЕ ИССЛЕДОВАНИЯ ЛЕКАРСТВ ДОКЛИНИЧЕСКИЕ /МЕТОДЫЖИДКОСТЬ-ЖИДКОСТНАЯ ЭКСТРАКЦИЯХРОМАТОГРАФИЯ ЖИДКОСТНАЯ /ИСПЖИВОТНЫЕ ЛАБОРАТОРНЫЕКРОЛИКИЦелью работы ...
Пивовар, М. Л.   +2 more
core  

Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure [PDF]

open access: yes, 2015
Background: Pulmonary hypertension is associated with poor outcome in patients with chronic heart failure (CHF) and may be a therapeutic target. Our aims were to develop a noninvasive model for studying pulmonary vasoreactivity in CHF and characterize ...
Ciobanu, Andrea   +12 more
core   +2 more sources

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