Results 71 to 80 of about 1,073,059 (362)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Silentiaires fin-de-siècle : émergence et épuisement d’un motif poétique
Quêtes Littéraires, 2017 The parallel urge of introspection and meditation which comes with the evocation of silence acts as landmark for a whole current of fin de siecle literature. The symbolist era gives the impression that its actors were obsessedwith silence.
Antoine Piantoni
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Absents et absences dans les Essais de Montaigne
Quêtes Littéraires, 2011 Except for Étienne de la Boétie, the friend for ever gone but whose presence pervades the Essais so vividly, the reader can notice the nearly total – and therefore puzzling – absence of Montaigne’s mother, Antoinette de Louppes, contrasting with the ...
Denis Bjaï
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Les silences dans la dramaturgie giralducienne
Quêtes Littéraires, 2017 Technical and rhetorical devices used by Giraudoux to indicate silence vary during its dramatic production. Silences have to do with relationships of the characters, both emotionally and dialogal, and are sometimes loaded the unspoken or unspeakable.
Françoise Bombard
doaj +1 more source
, 1991 Open worship is one of those traditions Friends embrace, but often we do so without much thought as to how to use the time meaningfully. The tendency is to be uncomfortable with too much silence and to fill the empty space with words.
Anderson, Paul
core
The collection of sententiae associated with the mimographer Publilius and its portrayal of laughter, tears, and silence [PDF]
, 2013 The purpose of this paper is two-fold: to provide an up-to-date overview of the main problems pertaining to the purpose and transmission of a collection of apophthegms (sententiae), associated with the mime-actor and mimographer Publilius, and to discuss
Panayotakis, Costas
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source