Results 51 to 60 of about 206,958 (317)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

“‘I will open my lips in vain’ (3.1.192): l’échec rhétorique dans Measure for Measure”

open access: yesSillages Critiques, 2013
Unlike other plays like King John, Richard III or most of the comedies, in which language is often presented as a powerful instrument of persuasion, Measure for Measure is a play that stages a number of ’’rhetorical failures’’. Though Isabella is said to
Mickaël Popelard
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Learner experience of silence in cohort-based distance education [PDF]

open access: yes, 2017
This study explores how distance learners experience the phenomenon of silence online. Guided by the primary research question – What are the lived experiences of online silence for learners who are members of distance learning communities?
Duran, Leslie
core  

Secrecy and Confession of Silence in Performance

open access: yesSymbolon, 2020
The creators of art play with the polarity of shown and hidden to attract the receptor of art in the alchemy of their opera. Crossing the borders of the words to the “unknown”, to the silence of the non-verbal performances, the public becomes connected ...
Daniel Meyer-Dinkgräfe   +1 more
doaj  

“All shadow and silence in it” (3.1.247-48): Reticence in Measure for Measure

open access: yesSillages Critiques, 2013
Measure for Measure’s notoriously ambivalent ending, particularly with Isabella’s lack of response to the Duke’s twice-repeated marriage proposal, has caused a wealth of critical comments. It seems that most critics have failed to notice that the silence
Denis Lagae-Devoldere
doaj   +1 more source

NHERF-2 silences the silencers [PDF]

open access: yesBlood, 2012
Hyperresponsiveness to growth factors underlies a wide variety of human diseases,including hemangiomas, the most common tumor of childhood. Hemangiomas have been found to be clonal neoplasms of endothelial cells, with somatic mutations in unknown genes likely to be responsible for their development.
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

“Don’t Keep It To Yourself!”: Digital Storytelling with South African Youth

open access: yesSeminar.net, 2010
As resources become available, the tools of digital storytelling are being introduced into a wide variety of contexts, with new projects involving youth emerging in increasingly remote areas throughout the developing world.
Amber Reed, Amy Hill
doaj  

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