Results 91 to 100 of about 259,814 (293)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
A.N. Tolstoy in the Journal Zavety (1912–1914) [PDF]
Studia LitterarumThe article examines the presence of Alexey Tolstoy in the context of the journal Zavety (1912–1914) and the reception of his early work by critics of this publication against the background of current assessments.
Natalia V. Novikova
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A silent unheard voice in the Old Testament: The Cushite woman whom Moses married in Numbers 12:1–10
In die Skriflig, 2018 Most of the time, women’s names are not mentioned, words are not put in their mouths or they are not allowed to say a word, and their achievements are behind the scene in the narratives.
David T. Adamo
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Writing Against the Silence: Female Poets in Postwar Spain and West Germany
Dictatorships & DemocraciesThe article takes a comparative approach to the writing of female poets in postwar Spain and West Germany, focusing on the ways in which the semantics of silence and writing as an explicit breaking of the silence are reflected within their literary ...
Jenny Augustin
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Silencers, silencing, and heritable transcriptional states
Microbiological Reviews, 1992 Three copies of the mating-type genes, which determine cell type, are found in the budding yeast Saccharomyces cerevisiae. The copy at the MAT locus is transcriptionally active, whereas identical copies of the mating-type genes at the HML and HMR loci are transcriptionally silent.
P, Laurenson, J, Rine
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Intro -- Foreword -- Preface -- Table of Contents -- List of Contributors -- List of Cases -- Table of Statutes -- PART I: THEORY AND METHODOLOGY -- 1. Silence and the Regulation of Misleading Conduct: A Taxonomy -- I.
Bant, Elise., Paterson, Jeannie.
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