Results 121 to 130 of about 1,711 (245)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The conspiracy of silence in families of the terminal oncological patients
Psicooncologia, 2008 The subject of ‘the conspiracy of silence’ is addressed following a bio-psycho-social model and taking into account current knowledge in the fields of psychooncology and palliative care, as well as research carried out both nationally and internationally.
Mª De Los Ángeles Ruiz-benítez de Lugo +1 more
doaj
Journal of NanobiotechnologyUlcerative colitis (UC) is a complex and chronic inflammatory bowel disease whose pathogenesis involves genetic and environmental factors, which poses a challenge for treatment.
Chenyang Cui +10 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Administrative Silence and Appeal Proccess [PDF]
, 2015 Ostvarivanje prava građana, odnosno rešavanje važnih životnih situacija zavisi često od organa uprave, što ukazuje na potrebu postojanja valjane uprave organizovane u skladu sa modernim evropskim načelima.
Dragić, Nada
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
The Sound of Silence: What Do We Know When Insiders Do Not Trade?
, 2012 We examine the phenomenon of insider silence, periods when corporate insiders do not trade. Our evidence strongly supports the jeopardy hypothesis that regulations inhibit insiders from trading on extreme information, implying a relation between insider ...
Ma, Qingzhong +3 more
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The Rail Infrastructure and Passenger Experience in Johannesburg
, 2023 A research report submitted in partial fulfillment of the requirements for the degree of Master of Business Administration to the Faculty of Commerce, Law and Management, Wits Business School, University of the Witwatersrand, Johannesburg, 2023Rail ...
Maluleke, Javulani Silence
core
Reforming Confession Law British Style: A Decade of Experience With Adverse Inferences from Silence
, 2000 In response to problems encountered in the administration of justice in Northern Ireland, the British government issued the Criminal Evidence (Northern Ireland) Order 1988 changing the character of how the right to silence and privilege against self ...
Berger, Mark
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source