Results 101 to 110 of about 1,711 (245)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
, 2019 Sistem zaštite od šutnje uprave u Republici Hrvatskoj zasnovan je na primjeni fikcije negativnog akta, a sadržan je u odredbama Zakona o općem upravnom postupku i Zakona o sporovima, dok se sustav pozitivne fikcije primjenjuje iznimno.
Baradić, Anđela
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Right of petition and administrative silence
, 2020 Con lamentable frecuencia, los funcionarios públicos que tienen a su cargo el ejercicio del poder público desoyen las peticiones de los gobernados por abstenerse de darles respuesta. En clara violación de su derecho de petición y de su derecho fundamental a una buena administración pública, ilícito que no sólo agravia el interés particular del ...
openaire +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
This Year’s Bioethicist: From Influencer to Prophetic Educator
Canadian Journal of BioethicsProfessional bioethicists have gained increasing acceptance in the healthcare and academic communities of the United States over the last 50 years.
Mark Kuczewski
doaj +1 more source
Governing student assessment: administrative rules, silenced academics and performing students
Assessment & Evaluation in Higher Education, 2011 In this paper, the author reports on an analysis of an Australian university’s assessment procedure. The procedure – a major governance document of the university – is deconstructed by way of a Foucauldian discourse analysis in order to consider how students and academics are governed. There were three major findings.
openaire +3 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
, 2022 Introduction: In the NICU, breastmilk is handled and administered as safely and carefully as a medication. Administration errors occur when incorrect breastmilk is administered to the wrong patient. This can lead to the transmission of infectious disease
Crociata, Lauren
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