Results 81 to 90 of about 1,711 (245)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Development, opportunities, and challenges of siRNA nucleic acid drugs
Small interfering RNA (siRNA) drugs were first proposed in 1999. They have reached the market for administration to patients after more than 20 years of development.
Bowen Xiao +9 more
doaj +1 more source
Review of Administrative Justice in the Republic of Kosovo
The present paper aims to provide a real view of adjudication of administrative cases in Kosovo. The issue of adjudication of administrative cases in the Republic of Kosovo remains a challenge following justice reforms which began in 2013 and are still ...
Islam Pepaj
doaj +1 more source
A Review of Organizational Silence antecedents and its impact on Job Attitudes [PDF]
In order to achieve the objective effectively and efficiently, employees are viewed as wellsprings of progress, innovation, learning and advancement. However a large number of them choose silence and not to pass on their profitable feelings and worries ...
Jahangir, Muhammad, Abdullah, Mehreen
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
BELMASK—An Audiovisual Dataset of Adversely Produced Speech for Auditory Cognition Research
In this article, we introduce the Berlin Dataset of Lombard and Masked Speech (BELMASK), a phonetically controlled audiovisual dataset of speech produced in adverse speaking conditions, and describe the development of the related speech task. The dataset
Cleopatra Christina Moshona +3 more
doaj +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Una de las obligaciones que la legislación vigente impone a la Administración es la de resolver los procedimientos administrativos, sin importar cuál sea la forma de iniciación de los mismos. Para hacer frente a la inactividad de la Administración que no
Villalba Puado, Laura
core
Pernikahan Subarang Ayie is a marriage that is held across the river in Lareh Sago Halaban District in which the marriage is doing illegally or siri, without any binding administration.
Aidil Alfin, Ali Rahman
doaj +1 more source

