Results 41 to 50 of about 1,711 (245)

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Irregularity Protection of Citizens' Constitutional Rights to the Administrative Silence

open access: yesJurnal Konstitusi, 2023
The Administrative's silence legally was an administrative error, however there are no standard to rule the mechanisms for protecting citizens against those an administrative error. This Research have two objectives. First of all, to analyze whether the changes of negative fictitional to positive fictitional are form of legal irregularity, secondly to ...
openaire   +3 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

THE IMPACT OF FORMAL AND INFORMAL INSTITUTIONS ON THE REPRESENTATION OF LEBANESE WOMEN IN SENIOR PUBLIC ADMINISTRATION POSITIONS [PDF]

open access: yes, 2022
Lebanese women remain underrepresented in politics in Lebanon in all parliament, cabinets and senior public administration. In Lebanon, the government has not achieved a gender quota policy in high level public administration positions nor in parliament ...
Al Bouery, Sarah
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

ADMINISTRATIVE SILENCE

open access: yes, 2021
Tema rada je šutnja uprave, radi se o situaciji u kojoj nadležno tijelo nije odlučilo o zahtjevu stranke koje traže određeno pravo u zakonom određenom roku.
Perša, Blaženka
core  

Le silence de l' Administration : recherche sur la décision implicite

open access: yes, 2021
Most of the research that has looked at the silence of the Administration is either very old or very quick on the notion, sometimes even both at the same time.
Desgree, Aurélien
core   +1 more source

Optimization of quorum quenching mediated bacterial attenuation of Solanum torvum root extract by response surface modelling through Box-Behnken approach

open access: yesJournal of Genetic Engineering and Biotechnology, 2018
The present study was intended to optimize the quorum sensing inhibitory action of Solanum torvum root extract against Chromobacterium violaceum. Factors such as bacterial density, frequency of administration and concentration of extract were analysed ...
Kayeen Vadakkan   +4 more
doaj   +1 more source

Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep

open access: yesJCI Insight, 2021
siRNAs comprise a class of drugs that can be programmed to silence any target gene. Chemical engineering efforts resulted in development of divalent siRNAs (di-siRNAs), which support robust and long-term efficacy in rodent and nonhuman primate brains ...
Chantal M. Ferguson   +17 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

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