Results 41 to 50 of about 36,922 (259)

Inclisiran, Low-Density Lipoprotein Cholesterol and Lipoprotein (a)

Pharmaceuticals, 2023
Dyslipidemia treatment is of major importance in reducing the risk of atherosclerotic cardiovascular disease (ASCVD), which is still the most common cause of death worldwide. During the last decade, a novel lipid-lowering drug category has emerged, i.e.,
Niki Katsiki, Michal Vrablik, Maciej Banach, Ioanna Gouni-Berthold   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Between emergency, submersion, and silence: LGBT as a research category in Administration [PDF]

Cadernos EBAPE.BR, 2020
Resumo Este artigo discute a adoção da sigla LGBT (lésbicas, gays, bissexuais, travestis e transexuais), questionando a representatividade dos grupos que fazem parte desse acrônimo nas pesquisas em Administração. No Brasil, afirma-se que, embora se almeje construir um campo de pesquisas no assunto, sua agenda é majoritariamente destinada às pesquisas ...
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Strategic Human Resource Management in Startups: A Catalyst for Entrepreneurial Growth in Emerging Asian Economics

Journal of Asia Entrepreneurship and Sustainability
This study examines Strategic Human Resource Management as a catalyst for entrepreneurial growth among startups in emerging Asian economies. The study focuses on two major dimensions: startup growth and human resource management effectiveness.
Sreejana Saha, Dr. Alok Kumar Bhargava, Dr. Ashutosh Goswami, Akshay Peter, Bhagiratha Sena, Dr. Kashmira Mathur   +5 more
doaj   +1 more source

The language of racism. Textual testimonies of Jewish-Arab hostility in the Israeli Academia

Ricerche di Pedagogia e Didattica, 2015
The persistent Jewish Arab conflict is present in every aspect of life in Israeli society and its echoes penetrate the everyday reality of higher educational institutions.
Tamar Heger, Saba Tufaha
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

La Administración no puede beneficiarse de su silencio

Revista Vasca de Administración Pública, 2010
If the Administration provokes legal uncertainty by means of a clearly illegal conduct, it cannot take advantage from that uncertainty by pretending to benefit vis-à-vis those that suffered the uncertainty generated from its silence.
Iñaki Agirreazkuenaga Zigorraga
doaj   +1 more source