Results 51 to 60 of about 1,711 (245)
Para Compreender a “Escravidão Moderna”: Vozes dos arquivos
Cadernos de Estudos Africanos, 2017 This paper examines the African experience with forced labor in colonial Mozambique, where the administration developed a labor regime that resembled a ‘modern slavery.’ Both contemporary observers and subsequent scholarly research have used the ...
Eric Allina
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Designing a defensive silence failure model of creative employees in organizations [PDF]
مدیریت و چشم انداز آموزشThe purpose of this research is to provide a model to break the defensive silence of creative employees in government organizations. In terms of purpose, the present research is applicable, and a mixed exploratory research of qualitative-quantitative ...
Azam Khosravi +2 more
doaj +1 more source
Inclisiran, Low-Density Lipoprotein Cholesterol and Lipoprotein (a)
Pharmaceuticals, 2023 Dyslipidemia treatment is of major importance in reducing the risk of atherosclerotic cardiovascular disease (ASCVD), which is still the most common cause of death worldwide. During the last decade, a novel lipid-lowering drug category has emerged, i.e.,
Niki Katsiki +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
, 2021 This study examines the strategic silence under President Muhammadu Buhari’s administration in Nigeria. Anchored on Shannon and Weaver mathematical model of communication and spiral of silence theory, the study beams a searchlight on instances of ...
Ate, Andrew Asan +2 more
core +1 more source
In Search of an Effective Model:A Comparative Outlook on Administrative Silence in Europe [PDF]
, 2020 Public administration inactivity, or in other words the excessive length of administrative proceedings, is not a new phenomenon; however, it appears to be of limited interest for comparative law, and it occurred particularly as attempts to develop a ...
Kovac, Polona +5 more
core +1 more source
Administrative Silence in Indonesia: Negative or Positive Legal Fiction?
Jurnal KonstitusiThe Government Administration Act introduced the positive legal-fiction model, apparently to replace the negative legal-fiction model under the State Administrative Courts Act.
Aan Efendi +4 more
doaj +1 more source