Results 11 to 20 of about 192,601 (302)

Suppressors of Meiotic Silencing by Unpaired DNA [PDF]

Non-Coding RNA, 2019
Meiotic silencing by unpaired DNA (MSUD) is a gene silencing process that occurs within meiotic cells of Neurospora crassa and other fungi. We have previously developed a high-throughput screen to identify suppressors of this silencing pathway.
Hua Xiao, Thomas M. Hammond, Patrick K. T. Shiu   +2 more
doaj   +3 more sources

Promoting virus-induced gene silencing of pepper genes by a heterologous viral silencing suppressor. [PDF]

Plant Biotechnol J, 2021
Zhou Y, Deng Y, Liu D, Wang H, Zhang X, Liu T, Wang J, Li Y, Ou L, Liu F, Zou X, Ouyang B, Li F.   +12 more
europepmc   +4 more sources

Oomycete pathogens encode RNA silencing suppressors [PDF]

Nature Genetics, 2013
Effectors are essential virulence proteins produced by a broad range of parasites, including viruses, bacteria, fungi, oomycetes, protozoa, insects and nematodes. Upon entry into host cells, pathogen effectors manipulate specific physiological processes or signaling pathways to subvert host immunity.
Qiao, Yongli, Liu, Lin, Xiong, Qin, Flores, Cristina, Wong, James, Shi, Jinxia, Wang, Xianbing, Liu, Xigang, Xiang, Qijun, Jiang, Shushu, Zhang, Fuchun, Wang, Yuanchao, Judelson, Howard S., Chen, Xuemei, Ma, Wenbo   +14 more
openaire   +3 more sources

Analysis of Pineapple Mealybug Wilt Associated Virus -1 and -2 for Potential RNA Silencing Suppressors and Pathogenicity Factors

Viruses, 2015
Higher plants use RNA silencing to defend against viral infections. As a counter defense, plant viruses have evolved proteins that suppress RNA silencing.
Kishore K. Dey, Wayne B. Borth, Michael J. Melzer, Ming-Li Wang, John S. Hu   +4 more
doaj   +1 more source

Enhancement of Recombinant Protein Production in Transgenic Nicotiana benthamiana Plant Cell Suspension Cultures with Co-Cultivation of Agrobacterium Containing Silencing Suppressors. [PDF]

, 2018
We have previously demonstrated that the inducible plant viral vector (CMViva) in transgenic plant cell cultures can significantly improve the productivity of extracellular functional recombinant human alpha-1-antiryspin (rAAT) compared with either a ...
Dandekar, Abhaya M, Falk, Bryce W, Huang, Ting-Kuo, McDonald, Karen A   +3 more
core   +3 more sources

Viral suppressors: Combatting RNA silencing [PDF]

Nature Plants, 2017
[EN] Plants defend themselves from invading viruses using RNA silencing. However, plant viruses try to spoil this defensive mechanism by expressing one or more proteins that act as RNA silencing suppressors. One such protein spoils plant defence by transporting the silencing signal into the peroxisomes to avoid its systemic spread.
openaire   +5 more sources

Constrained peptides mimic a viral suppressor of RNA silencing [PDF]

Nucleic Acids Research, 2021
Abstract The design of high-affinity, RNA-binding ligands has proven very challenging. This is due to the unique structural properties of RNA, often characterized by polar surfaces and high flexibility. In addition, the frequent lack of well-defined binding pockets complicates the development of small molecule binders.
Arne Kuepper, Niall M McLoughlin, Saskia Neubacher, Alejandro Yeste-Vázquez, Estel Collado Camps, Chandran Nithin, Sunandan Mukherjee, Lucas Bethge, Janusz M Bujnicki, Roland Brock, Stefan Heinrichs, Tom N Grossmann   +11 more
openaire   +6 more sources

Identification of Pns6, a putative movement protein of RRSV, as a silencing suppressor

Virology Journal, 2010
RNA silencing is a potent antiviral response in plants. As a counterdefense, most plant and some animal viruses encode RNA silencing suppressors. In this study, we showed that Pns6, a putative movement protein of Rice ragged stunt virus (RRSV), exhibited
Lin Qiying, Wu Zujian, Hu Meiqun, Cai Lijun, Wang Chunzheng, Du Zhenguo, Wu Jianguo, Li Yi, Xie Lianhui   +8 more
doaj   +1 more source

The NS3 protein of rice hoja blanca virus suppresses RNA silencing in mammalian cells [PDF]

, 2008
The NS3 protein of the tenuivirus rice hoja blanca virus (RHBV) has previously been shown to represent the viral RNA interference (RNAi) suppressor and is active in both plant and insect cells by binding short interfering RNAs (siRNAs) in vitro.
Goldbach, R.W., Hemmes, J.C., Prins, M.W., Schnettler, E.   +3 more
core   +2 more sources

Tomato Spotted Wilt Virus NSs Protein Supports Infection and Systemic Movement of a Potyvirus and Is a Symptom Determinant

Viruses, 2018
Plant viruses are inducers and targets of antiviral RNA silencing. To condition susceptibility, most plant viruses encode silencing suppressor proteins that interfere with antiviral RNA silencing.
Hernan Garcia-Ruiz, Sergio M. Gabriel Peralta, Patricia A. Harte-Maxwell   +2 more
doaj   +1 more source