Results 291 to 300 of about 281,837 (328)

AMPA-silent synapses in brain development and pathology

Nature Reviews Neuroscience, 2013
Synapses are constantly generated at a high rate in the developing, prepubescent brain. Newly generated glutamatergic synapses lack functional AMPA receptor-mediated transmission. Most of these 'AMPA-silent' synapses are eliminated during the developmental period, but some are specifically selected for AMPA unsilencing by correlated pre-and ...
Eric, Hanse, Henrik, Seth, Ilse, Riebe
openaire   +2 more sources

Creation of AMPA-silent synapses in the neonatal hippocampus

Nature Neuroscience, 2004
In the developing brain, many glutamate synapses have been found to transmit only NMDA receptor-mediated signaling, that is, they are AMPA-silent. This result has been taken to suggest that glutamate synapses are initially AMPA-silent when they are formed, and that AMPA signaling is acquired through activity-dependent synaptic plasticity.
Min-Yi, Xiao, Pontus, Wasling, Eric, Hanse, Bengt, Gustafsson   +3 more
openaire   +2 more sources

Evidence for presynaptically silent synapses in the immature hippocampus

Biochemical and Biophysical Research Communications, 2017
Silent synapses show NMDA receptor (NMDAR)-mediated synaptic responses, but not AMPAR-mediated synaptic responses. A prevailing hypothesis states that silent synapses contain NMDARs, but not AMPARs. However, alternative presynaptic hypotheses, according to which AMPARs are present at silent synapses, have been proposed; silent synapses show slow ...
Jae Young, Yoon, Sukwoo, Choi
openaire   +2 more sources

Silent glutamatergic synapses and nociception in mammalian spinal cord

Nature, 1998
Neurons in the superficial dorsal horn of the spinal cord are important for conveying sensory information from the periphery to the central nervous system. Some synapses between primary afferent fibres and spinal dorsal horn neurons may be inefficient or silent.
P, Li, M, Zhuo
openaire   +2 more sources

Hippocampal long term potentiation: silent synapses and beyond

Journal of Physiology-Paris, 2003
Long-term, activity-driven synaptic plasticity allows neuronal networks to constantly and durably adjust synaptic gains between synaptic partners. These processes have been proposed to serve as a substrate for learning and memory. Long-term synaptic potentiation (LTP) has been observed at many central excitatory synapses and perhaps most extensively ...
openaire   +2 more sources

The Carotid Body "Tripartite Synapse": Role of Gliotransmission.

Advances in Experimental Medicine and Biology, 2023
E. Leonard, C. Nurse
semanticscholar   +1 more source

Silent synapse: A new player in visual cortex critical period plasticity

Pharmacological Research, 2019
Xiaojie Huang
semanticscholar   +1 more source

An optoelectronic synapse based on α-In2Se3 with controllable temporal dynamics for multimode and multiscale reservoir computing

Nature Electronics, 2022
Lin Bao, Ru Huang, Yuchao Yang
exaly  

Silent Synapse

2023
openaire   +1 more source

Silent Synapse

2022
openaire   +1 more source