Results 221 to 230 of about 941,591 (294)

Novel Interdigitated Electrode Conductometric Sensor for Rapid, Sensitive, and Selective Detection of cTnI Biomarkers in Saliva

Advanced NanoBiomed Research, EarlyView.
A miniaturized high resistivity silicon‐based interdigitated conductometric sensor detects cTnI at sub‐femtomolar levels with high selectivity. The device enables noninvasive testing using artificial and pooled human saliva in real‐time electrical readings. This portable biosensor offers a promising futuristic medical device providing new opportunities
Preethi Chidambaram, Fateme Akhlaghi Bagherjeri, Ganganath S. Perera, Rajour Tanyi Ako, Sreekanth S. P, Chenglong Xu, Sharath Sriram, Shanmuga Sundar Dhanabalan, Madhu Bhaskaran   +8 more
wiley   +1 more source

Patient‐Personalized Membrane‐Coated Magnetic Nanovectors: Probing the Biomimetic Interface for Targeted Tumor Theranostics

Advanced NanoBiomed Research, EarlyView.
This study presents a label‐free spectroscopic platform to evaluate membrane protein conformation on patient‐derived glioblastoma cell membrane‐coated magnetic nanovectors. This work demonstrates that preserving membrane protein integrity during nanoparticle fabrication enhances homotypic tumor targeting and reduces hard protein corona formation ...
Daniele De Pasquale, Michela Patrucco, Melike Belenli Gümüş, Alessandra Flori, Luca Menichetti, Stefania Moscato, Valentina Bonanni, Alessandra Gianoncelli, Milan Žižić, Pietro Fiaschi, Monica Truffelli, Andrea Bianconi, Melis Emanet, Gianmarco Ferri, Chiara Maria Mazzanti, Carlotta Pucci, Gianni Ciofani   +16 more
wiley   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

A simple and efficient synthesis of 5-hydroxymethylfurfural from carbohydrates using acidic ionic liquid grafted on silica gel. [PDF]

RSC Adv
Doan VTC, Dao TM, Huynh TA, Nguyen TT, Tran PH.   +4 more
europepmc   +1 more source

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

Angewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao, Leyao Chen, Karin Steffen, Henrik Schweder, Birgit Schreckenberger, Shu‐Ming Li, Ben Auxier, Antonis Rokas, Reinhard Fischer   +8 more
wiley   +1 more source

Macrocyclization of ω‐Isocyano Aldehydes

Angewandte Chemie, EarlyView.
The ω‐isocyano aldehydes readily undergo cyclization to afford α‐acyloxy, α‐hydroxy, α‐acetamido, and α‐keto macrolactams, as well as tetrazole‐fused macrocycles, via C(sp3)─C(sp2) bond formation, providing access to diverse α‐functionalized medium‐sized lactams and macrolactams. ABSTRACT Medium‐sized rings and macrocycles constitute a privileged class
Baochao Yang, Teerawat Songsichan, Cyril Piemontesi, Qian Wang, Jieping Zhu   +4 more
wiley   +1 more source

Sequence‐Controlled Helical Ladder Polymers: Impact of Stereochemical Sequence on Helical Geometry and Chiral Recognition

Angewandte Chemie, EarlyView.
Nature programs distinct secondary structures and functions through subtle stereochemical differences, as exemplified by amylose and cellulose. Translating this principle into synthetic ladder polymers, stereochemical sequence control gives rise to diastereomeric coil‐ and ribbon‐type helices with complementary chiral recognition, demonstrating ...
Tomoyuki Ikai, Kanta Wakabayashi, Masaya Yoshida, Kosuke Oki, Eiji Yashima   +4 more
wiley   +1 more source

Al(SO₄)(OH)·5H₂O Stemming from Complexation of Aluminum Sulfate with Water-Soluble Ternary Copolymer and further Stabilized by Silica Gel as Effective Admixtures for Enhanced Mortar Cementing. [PDF]

Materials (Basel)
Song Z, Bibi Z, Chaudhary S, Jia Q, Li X, Sun Y.   +5 more
europepmc   +1 more source

Synthesis of Ladder and Flexible Polysulfonimides Directly From Anionic Monomers: Investigating Structure–Property Convergence in Succinonitrile–Polymer Electrolyte Blends

Angewandte Chemie, EarlyView.
Direct synthesis of sulfonimide‐based polymers of intrinsic microporosity enables comparison with compositionally similar flexible analogs. Incorporation of a common pore‐filling transport medium drives these fundamentally different polymer architectures toward similar bulk conductivity and mechanical properties while revealing distinct microscopic ion‐
Abraham Herzog‐Arbeitman, Pablo Leon, Benedikt S. Schreib, KyuJung Jun, Jurgis Ruza, Vanesa Munoz Perales, Yang Shao‐Horn, Rafael Gomez‐Bombarelli, Jeremiah A. Johnson   +8 more
wiley   +1 more source

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

Angewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani, Paritosh Dey, Nicholas H. Stillman, Daniel M. Andrade, Michal Šimek, Martin Dračínský, Daniel Bím, Paulo H. S. Paioti   +7 more
wiley   +1 more source