Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner +10 more
wiley +1 more source
Foreign body reaction: towards a macrophage-centered adverse outcome pathway for fibrotic encapsulation. [PDF]
Meseberg T, Kurz S, Spohn J.
europepmc +1 more source
BLOC: Buildable and Linkable Organ on a Chip
We developed a “Buildable and Linkable Organ on a Chip” (BLOC) that can construct diverse microphysiological systems (MPSs). The BLOC is standardized to the same size and has one of the functions of “Culture,” “Control,” or “Analysis.” Users can freely configure various MPSs, including developing perfusion, cytotoxicity analysis, and biochemical ...
Yusuke Kimura +7 more
wiley +1 more source
Material and Technological Advancements in the Recontouring of Maxillofacial, Somatic, and Dental Structures and Their Implications for Auricular Prosthesis: A Case Report. [PDF]
Kumar A +5 more
europepmc +1 more source
Light Switchable Ionic Conductivity of Arylazopyrazole Modified Polysiloxanes
We present a polysiloxane functionalized with a novel arylazopyrazole dye that undergoes reversible photoisomerization. Upon lithium bis(trifluoromethanesulfonyl)imide addition and UV irradiation, the polymer exhibits a shift in tan(d) toward higher frequencies and enhanced ionic conductivity.
Malte S. Beccard +7 more
wiley +1 more source
The Influence of Mixing Speed on the Physicomechanical Parameters of Polyaddition Poly(dimethylsiloxanes) with Fillers. [PDF]
Chmielnicka E +2 more
europepmc +1 more source
Anti‐Slip Material‐Based Strategies and Approaches
This review highlights the principle mechanisms of slipping at the microscale, linking contact mechanics with a friction behavior model for surface interfaces. Main strategies to develop anti‐slip properties to the surfaces are discussed alongside standardized testing approaches.
Sogand Abbaspoor‐Zanjani +3 more
wiley +1 more source
The influence of tantalum oxide nanoparticle on thermal conductivity and tear strength after addition on maxillofacial silicone. [PDF]
Ali Mousa S, Abdullah ZS.
europepmc +1 more source
Ductility Tuning via Cluster Network Characteristics of Porous Components
Network optimization via cluster characteristics induced by interaction of stress concentration is proposed, demonstrating increased cluster size and dispersion in non‐uniform porous components. The optimized structures exhibit, for the first time, that enhanced ductility and damage progression is controllable through zigzag cluster network designed by
Ryota Toyoba +4 more
wiley +1 more source
3D Printing of Strong and Room-Temperature Reprocessable Silicone Vitrimers. [PDF]
Menasce S +3 more
europepmc +1 more source

