Results 201 to 210 of about 44,667 (255)
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Targeting STING-mediated pro-inflammatory and pro-fibrotic effects of alveolar macrophages and fibroblasts blunts silicosis caused by silica particles.

Journal of Hazardous Materials, 2023
Silica is utilized extensively in industrial and commercial applications as a chemical raw material, increasing its exposure and hazardous potential to populations, with silicosis serving as an important representative.
L. Ou   +7 more
semanticscholar   +1 more source

SILICOSIS.

Lancet, The, 1932
exaly   +2 more sources

Update on Silicosis.

Surgical Pathology Clinics, 2023
Although silicosis has been an established disease with a recognized cause for more than 100 years, many workers continue to be exposed to silica and new outbreaks of disease continue to occur.
A. Churg, Nestor L Muller
semanticscholar   +1 more source

Atractylenolide III Ameliorated Autophagy Dysfunction via Epidermal Growth Factor Receptor-Mammalian Target of Rapamycin Signals and Alleviated Silicosis Fibrosis in Mice.

Laboratory investigation; a journal of technical methods and pathology, 2023
Atractylenolide III (ATL-III) is a major active constituent of the natural plant Atractylodes rhizome. Our previous study has shown that ATL-III may alleviate alveolar macrophage apoptosis via the inhibition of the mammalian target of rapamycin (mTOR ...
Shiyi Tan   +6 more
semanticscholar   +1 more source

Celastrol as a candidate drug for silicosis: From bioinformatics and network pharmacology to experimental validation.

International Immunopharmacology, 2023
Silicosis, a highly lethal occupational respiratory disease characterized by irreversible pulmonary fibrosis, remains challenging to treat due to its unclear pathogenesis.
Chao Liang   +9 more
semanticscholar   +1 more source

Subradiological silicosis

American Journal of Industrial Medicine, 2018
AbstractThe purpose of this commentary is to bring the neglected phenomenon of subradiological silicosis and its implications to the attention of readers. We define subradiological silicosis as silicosis detectable on pathological examination of lung tissue but not visible radiologically.
Rodney Ehrlich, Jill Murray, David Rees
openaire   +2 more sources

SILICOSIS

Clinics in Chest Medicine, 1992
Silicosis is an ancient disease, but with modern understanding of safe levels of exposure, it should be a vanishing disease. Emphasis will be placed on newer concepts in the pathogenesis of the disease and the health effects of low levels of quartz dust in relation to current exposure standards.
openaire   +2 more sources

Silicosis.

Wiener medizinische Wochenschrift (1946), 2000
Abstract Quartz, the crystalline form of silicon dioxide (SiO2), is the most common constituent of the earth’s crust and workers exposed to quartz all over the world are at risk of developing silicosis. High-risk industries include: mining; quarrying; tunneling; abrasive blasting; monument engraving; working in a foundry ...
Kenneth D Rosenman, Mary Jo Reilly
openaire   +3 more sources

Repeated silica exposures lead to silicosis severity via PINK1/PARKIN mediated mitochondrial dysfunction in mice model.

Cellular Signalling
BACKGROUND AND OBJECTIVES Silicosis, one of the occupational health illnesses is caused by inhalation of crystalline silica. Deposition of extracellular matrix and fibroblast proliferation in lungs are linked to silicosis development.
Sneha Kumari, Payal Singh, Rashmi Singh
semanticscholar   +1 more source

Mechanics-activated fibroblasts promote pulmonary group 2 innate lymphoid cell plasticity propelling silicosis progression

Nature Communications
Crystalline silica (CS) particle exposure leads to silicosis which is characterized as progressive fibrosis. Fibroblasts are vital effector cells in fibrogenesis.
Yangyang He   +9 more
semanticscholar   +1 more source

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