Results 211 to 220 of about 41,841 (256)
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Another One Fights the Dust - Targeting the NLRP3 Inflammasome for the Treatment of Silicosis.

American Journal of Respiratory Cell and Molecular Biology, 2022
Silicosis is a multifaceted lung disease, characterised by persistent inflammation and structural remodelling. Despite its poor prognosis, there are no treatments currently available for patients with silicosis.
M. Lam, A. Mansell, M. Tate
semanticscholar   +1 more source

Engineering solutions to breath tests based on an e-nose system for silicosis screening and early detection in miners

Journal of Breath Research, 2022
This study aims to develop an engineering solution to breath tests using an electronic nose (e-nose), and evaluate its diagnosis accuracy for silicosis. Influencing factors of this technique were explored.
Wu Xuan   +5 more
semanticscholar   +1 more source

Silicosis

The Lancet, 2012
Silicosis is a fibrotic lung disease caused by inhalation of free crystalline silicon dioxide or silica. Occupational exposure to respirable crystalline silica dust particles occurs in many industries. Phagocytosis of crystalline silica in the lung causes lysosomal damage, activating the NALP3 inflammasome and triggering the inflammatory cascade with ...
Chi Chiu, Leung   +2 more
openaire   +2 more sources

Altered M1/M2 polarization of alveolar macrophages is involved in the pathological responses of acute silicosis in rats in vivo

Toxicology and industrial health, 2022
Alveolar macrophages play a vital role in the development of acute silicosis, but the dynamic changes of M1 and/or M2 phenotypes have not been elucidated. In this study, acute silicosis models of rat were established by a one-time dusting method, and the
Zhao-qiang Zhang   +5 more
semanticscholar   +1 more source

Silicosis and autoimmunity

Current Opinion in Allergy & Clinical Immunology, 2017
Purpose of reviewOf the various environmental, occupational, and medical substances that cause dysregulation of autoimmunity, the effects and causative mechanisms of silica particles and asbestos fibers are discussed in this review.Recent findingsWith respect to silica, many epidemiological studies have shown a significant association between silica ...
Hiroaki Hayashi   +4 more
openaire   +2 more sources

Silicosis in the 1990s

Chest, 1997
To describe state-based surveillance for silicosis that estimates prevalence of this condition, describes characteristics of affected individuals, and targets public health interventions.The data presented are a case series of patients with silicosis reported to a state health department.
Mary Jo Reilly   +3 more
openaire   +3 more sources

Silicosis in the 1980's

American Industrial Hygiene Association Journal, 1981
At the request of the Mine Safety and Health Administration (MSHA), the National Institute for Occupational Safety and Health (NIOSH) recently investigated the health of workers at two silica flour mills. Both mills have a long history of failure to maintain workplace concentrations of dust containing free silica below the MSHA exposure standard ...
Daniel E. Banks   +2 more
openaire   +3 more sources

SILICOSIS

Clinics in Chest Medicine, 1992
Silicosis is an ancient disease, but with modern understanding of safe levels of exposure, it should be a vanishing disease. Emphasis will be placed on newer concepts in the pathogenesis of the disease and the health effects of low levels of quartz dust in relation to current exposure standards.
openaire   +2 more sources

Subradiological silicosis

American Journal of Industrial Medicine, 2018
AbstractThe purpose of this commentary is to bring the neglected phenomenon of subradiological silicosis and its implications to the attention of readers. We define subradiological silicosis as silicosis detectable on pathological examination of lung tissue but not visible radiologically.
Rodney Ehrlich, Jill Murray, David Rees
openaire   +2 more sources

What is silicosis?

Tubercle, 1934
Summary (1) The essential agent in the causation of true or ‘classical’ silicosis, as distinguished from non-specific pneumoconiosis, is the freshly-cloven silica particle. (2) The pathological process basically consists in the hydration of the silica particle at the expense of the cell protoplasm.
openaire   +3 more sources

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