Results 51 to 60 of about 8,180 (164)

Clinical usefulness of serum angiotensin converting enzyme in silicosis

Pulmonology
Introduction Silicosis is an irreversible and incurable disease. Preventive measures to eliminate exposure are the only effective way to reduce morbidity and mortality.
J. Blanco-Pérez, Á. Salgado-Barreira, S. Blanco-Dorado, M.E. González Bello, A.C. Caldera Díaz, A. Pérez-Gonzalez, A. Pallarés Sanmartín, A. Fernández Villar, F.J. Gonzalez-Barcala   +8 more
doaj   +1 more source

A novel circRNA-SNP may increase susceptibility to silicosis

Ecotoxicology and Environmental Safety, 2022
In this study, we aimed to reveal the association between circRNA-related single nucleotide polymorphisms (SNPs) with the susceptibility of silicosis.
Zhounan Cheng, Yingyi Zhang, Rui Zhao, Yan Zhou, Yang Dong, Anni Qiu, Huiwen Xu, Yiran Liu, Wendi Zhang, Qing Chang, Minjie Chu   +10 more
doaj  

Immunological Features and Potential Biomarkers of Systemic Sclerosis–Associated Interstitial Lung Disease and Idiopathic Pulmonary Fibrosis

The Clinical Respiratory Journal, Volume 19, Issue 4, April 2025.
The results revealed that the CD4+/CD8+ T cell ratio of pbmc in SSc‐ILD patients was significantly higher than in SSc‐nonILD patients. In IPF patients, an elevated CD4+/CD8+ T cell ratio was also observed in progressive group, and Treg and mature CD4 + T cells might cause this change.
Shuai Shao, Siyu Cao, Yusha Chen, Zhijin Zhang, Tong Zhaohui   +4 more
wiley   +1 more source

Safety and efficacy of a feed additive consisting of Kieselguhr (diatomaceous earth) for all animal species (Imerys France)

EFSA Journal, Volume 23, Issue 4, April 2025.
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of Kieselguhr (diatomaceous earth, three forms: natural, purified calcined and purified flux‐calcined) as a technological additive (functional group: anticaking and binder) for all animal species.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Ilen Röhe, Katerina Theodoridou, Vasileios Bampidis, Noël Dierick, Ruud Woutersen, Maria de Lourdes Bastos, Fernando Ramos, Jaume Galobart, Maria Vittoria Vettori, Orsolya Holczknecht, Jordi Ortuño, Fabiola Pizzo, Piera Valeri, Matteo L. Innocenti, Angelica Amaduzzi   +29 more
wiley   +1 more source

CC-chemokine ligand 18, CXC motif chemokine 13 and osteopontin as biomarkers of silicosis and asbestosis: a prospective observational study

Scientific Reports
Background Silicosis and asbestosis, distinct forms of pneumoconiosis, manifest progressive interstitial fibrosis due to exposure to silica dust or asbestos fibers. This study aimed to identify potential biomarkers for diagnosing silicosis and asbestosis,
Na Wu, Changjiang Xue, Shiwen Yu, Yuanying Wang, Di Sun, Qiao Ye   +5 more
doaj   +1 more source

The regulatory effect of pulmonary lymphatic drainage on silicosis fibrosis

Ecotoxicology and Environmental Safety, 2022
Silicosis is a fibrotic disease caused by long-term inhalation of SiO2 particles that currently has no effective treatment. Earlier studies have suggested that pulmonary lymphatic vessels play a key role in the transport of silica but have not address ...
Jie Cui, Hailan He, Hong Xu, Ziying Chen, Jingsi Wang, Yi Liu, Xiaohui Hao, Lingli Guo, Heliang Liu, Hongli Wang   +9 more
doaj  

Genome-wide mRNA profiling identifies the NRF2-regulated lymphocyte oxidative stress status in patients with silicosis

Journal of Occupational Medicine and Toxicology, 2021
Background The immunomodulatory abnormalities of silicosis are related to the lymphocyte oxidative stress state. The potential effect of antioxidant therapy on silicosis may depend on the variation in nuclear factor erythroid 2-related factor 2 (NRF2 ...
Yingzheng Zhao, Guangcui Xu, Haibin Li, Meiyu Chang, Cheng Xiong, Yingjun Tao, Yi Guan, Yuchun Li, Sanqiao Yao   +8 more
doaj   +1 more source

Silica, Silicosis, and Autoimmunity [PDF]

Frontiers in Immunology, 2016
Inhalation of dust containing crystalline silica is associated with a number of acute and chronic diseases including systemic autoimmune diseases. Evidence for the link with autoimmune disease comes from epidemiological studies linking occupational exposure to crystalline silica dust with the systemic autoimmune diseases systemic lupus erythematosus ...
openaire   +4 more sources

Identifying and Prioritizing Hazardous Chemicals in Construction Metal Structure Coating Systems: A Roadmap for Data‐Driven Disease Prevention

American Journal of Industrial Medicine, Volume 68, Issue S1, Page S23-S44, March 2025.
ABSTRACT Introduction Occupational exposure as a painter was classified by the International Agency for Research on Cancer (IARC) as a Group 1 carcinogen (carcinogenic to humans) in 1989. Chemical agents responsible for cancers and other illnesses among industrial painters are not well‐documented. The goal of this systematic review and synthesis was to
Paridhi Patel, Dhimiter Bello, Anila Bello   +2 more
wiley   +1 more source

OC-STAMP is a potential biomarker and therapeutic target for Silicosis: an exploratory investigation

Journal of Translational Medicine
Background Silicosis, a disease characterized by fibrous changes in lung tissue due to prolonged silica dust inhalation, exhibits a complex pathogenesis that remains inadequately addressed by current interventions.
Jing Wu, Bingyu Zhang, Wei Du, Yimin Shi, Chunhong Xie, Yanyan Ke, Xue Yi   +6 more
doaj   +1 more source