Results 151 to 160 of about 4,863 (192)

Chimeric antigen receptor T-cell therapy associated hemophagocytic lymphohistiocytosis syndrome: clinical presentation, outcomes, and management. [PDF]

open access: yesBlood Cancer J
Khurana A   +24 more
europepmc   +1 more source

Targeting the JAK/STAT Signaling Pathway in Breast Cancer: Leaps and Hurdles. [PDF]

open access: yesBiomedicines
Aho S   +7 more
europepmc   +1 more source

Clinical Development of Siltuximab

Current Oncology Reports, 2015
Siltuximab is a chimeric monoclonal antibody targeting interleukin-6 (IL-6), which in the fall of 2014 became the first FDA-approved treatment of the rare disease idiopathic multicentric Castleman's disease (MCD). MCD is a non-clonal lymphoproliferative disorder in which common symptoms include fever, night sweats, weight loss, and fatigue.
Christine C, Davis   +2 more
openaire   +2 more sources

Siltuximab: First Global Approval

Drugs, 2014
The anti-interleukin-6 (IL-6) chimeric monoclonal antibody siltuximab is the first drug to be approved for the treatment of multicentric Castleman's disease (MCD) in the US and European union (EU), having gained approval under the FDA priority review program in the US and from an accelerated assessment and recommendation by the Committee for Medicinal ...
Anthony, Markham, Trina, Patel
openaire   +2 more sources

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