Results 21 to 30 of about 4,863 (192)

Long-term tolerance and efficacy of siltuximab (anti-IL-6) in a young adult with idiopathic multicentric Castleman disease during COVID-19

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2023
Background: Castleman disease (CD) is a rare lymphoproliferative disorder with various subtypes, including the HHV-8-negative/idiopathic multicentric CD (iMCD).
Helbies Bedier   +3 more
doaj   +1 more source

Idiopathic Multicentric Castleman Disease Occurring Shortly after mRNA SARS-CoV-2 Vaccine

open access: yesVaccines, 2022
Idiopathic Multicentric Castleman Disease (iMCD) is a potentially life-threatening systemic disease whose complex symptomatology is due to cytokine dysregulation.
Christian Hoffmann   +7 more
doaj   +1 more source

Repurposing Interleukin-6 Inhibitors to Combat COVID-19. [PDF]

open access: yes, 2020
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is a pandemic with major implications across the world. One of the most frequent causes of death from SARS-CoV-2 is fatal pneumonia from coronavirus disease 2019 (COVID-19), which is associated
Kato, Shumei, Kurzrock, Razelle
core   +1 more source

CXCL13 is a predictive biomarker in idiopathic multicentric Castleman disease

open access: yesNature Communications, 2022
Idiopathic multicentric Castleman disease (iMCD) is a life-threatening inflammatory disease requiring immediate intervention, for which the recommended first-line therapy is the Interleukin-6 pathway inhibitor siltuximab.
Sheila K. Pierson   +11 more
doaj   +1 more source

Idiopathic Multicentric Castleman Disease following SARS-CoV-2 Vaccination

open access: yesJournal of Cancer Research and Practice, 2023
Idiopathic multicentric Castleman disease (iMCD) is a rare lymphoproliferative disorder. The preferred primary treatment for iMCD is siltuximab, an anti-interleukin-6 antibody (anti–IL-6).
Chien-Yu Ker   +3 more
doaj   +1 more source

Potential Immunological Treatments in COVID-19 Patients

open access: yesDüzce Tıp Fakültesi Dergisi, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seemed in Wuhan, China in December 2019. SARS-CoV-2 infection in human was named as coronavirus disease 2019 (COVID-19).
Muhammet Mesut Nezir Engin   +1 more
doaj   +1 more source

A challenging diagnosis of idiopathic multicentric Castleman disease with complex systemic presentation: A case report

open access: yesClinical Case Reports, 2023
Key Clinical Message Idiopathic multicentric Castleman disease (iMCD) is challenging to diagnose due to clinical similarities with other conditions, such as Still's disease.
Magdalena Strach   +3 more
doaj   +1 more source

Immune-related adverse events of biological immunotherapies used in COVID-19

open access: yesFrontiers in Pharmacology, 2022
The use of biological immunotherapeutic drugs is one of the options currently being evaluated and employed to manage COVID-19, specifically monoclonal antibodies, which have shown benefit by regulating the excessive immune response seen in patients with ...
Daniela Baracaldo-Santamaría   +5 more
doaj   +1 more source

TAFRO Syndrome and Elusive Diagnosis of Idiopathic Multicentric Castleman Disease Treated with Empiric Anti-Interleukin-6 Therapy

open access: yesCase Reports in Oncology, 2021
TAFRO syndrome is defined by the presence of thrombocytopenia (T), anasarca (A), fever (F), reticulin fibrosis/renal dysfunction (R), and organomegaly (O) and can be seen with idiopathic multicentric Castleman disease (iMCD) or as an isolated process ...
Corinne Williams   +5 more
doaj   +1 more source

POEMS Syndrome: Presented as Idiopathic Multicentric Castleman Disease of Plasma Cell Variant for Eight Years and Dramatic Treatment with Siltuximab Followed by Autologous Peripheral Blood Stem Cell Transplantation

open access: yesDiagnostics, 2022
Background: POEMS syndrome (POEMS) is a rare plasma cell clonal paraneoplastic syndrome consisting of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes presenting with idiopathic multicentric Castleman disease (iMCD ...
Yong-Moon Lee   +2 more
doaj   +1 more source

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