Results 51 to 60 of about 19,240 (226)

Silybum marianum: Beyond Hepatoprotection. [PDF]

open access: yes, 2015
Silybum marianum is a medicinal plant that has long been used as hepatoprotective remedy. It has been used for the treatment of numerous liver disorders characterized by functional impairment or degenerative necrosis.
Bahmani, M.   +3 more
core   +1 more source

Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
wiley   +1 more source

Evaluation of Liver Damage and Herbal Detoxification of Coral Reef Fish Caused by Ammonia Stress

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 3, June 2026.
Slybum marianum can reduce ammonia stress and enhance liver protection in marine fish. ABSTRACT Ammonia nitrogen can cause serious toxicological damage to fish and cause fish death. This study focused on liver damage caused by ammonia nitrogen stress in coral reef fish and used herbal extracts to improve ammonia poisoning and prevent liver tissue ...
Wei‐Ting Sun   +3 more
wiley   +1 more source

Multitargeted therapy of cancer by silymarin [PDF]

open access: yesCancer Letters, 2008
Silymarin, a flavonolignan from milk thistle (Silybum marianum) plant, is used for the protection against various liver conditions in both clinical settings and experimental models. In this review, we summarize the recent investigations and mechanistic studies regarding possible molecular targets of silymarin for cancer prevention.
Kumaraguruparan, Ramasamy   +1 more
openaire   +2 more sources

Effect of oral silymarin on liver function in pediatric acute lymphoblastic leukemia in the maintenance phase: a double-blind randomized clinical trial

open access: yesFrontiers in Pharmacology
Introduction: Liver dysfunction is one of the most common disorders in patients with acute lymphoblastic leukemia (ALL). In recent studies, silymarin has been observed to have hepatic protective effects.
Aziz Eghbali   +6 more
doaj   +1 more source

Estimation of the novel antipyretic, anti-inflammatory, antinociceptive and antihyperlipidemic effects of silymarin in Albino rats and mice

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2015
Objective: To evaluate the other pharmacological actions of silymarin in Albino rats and mice such as antipyretic, anti-inflammatory, antinociceptive and antihyperlipidemic effects.
Mohamed Mahmoud Amin   +1 more
doaj   +1 more source

Effect of silymarin on blood coagulation profile and osmotic fragility in carbon tetrachloride induced hepatotoxicity in male Wistar rats

open access: yesToxicology Reports, 2022
Reports about the impact of Carbon tetrachloride (CCl4) hepatotoxicity on coagulation profile have been inconsistent. Multiple investigators have however demonstrated the effectiveness of silymarin in the resolution of anomalies induced by CCl4, although
Aminat Bolanle Popoola   +3 more
doaj   +1 more source

Digestive enzymes activity and growth indices of rainbow trout (Oncorhynchus mykiss) fed diets supplemented with silymarin and Nickle Oxide nanoparticles [PDF]

open access: yes, 2016
There is growing concern regarding nano-sized material discharge into water bodies and their subsequent toxicity to aquatic lives owing to increasingly rapid development and industrial applications of nanoparticles.
Imani, A.   +3 more
core  

Acute toxicity of arsenic and oxidative stress responses in the embryonic development of the common South American toad Rhinella arenarum [PDF]

open access: yes, 2015
Arsenic (As), a natural element of ecological relevance, is found in natural water sources throughout Argentina in concentrations between 0.01mg/L and 15mg/L. The autochthonous toad Rhinella arenarum was selected to study the acute toxicity of As and the
Adams   +37 more
core   +1 more source

Development and Optimization of a Nanophytosomes‐Based Thermogel as a Topical Anti‐Psoriatic for Increased Solubility and Bioavailability

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Schematic illustration of the development, optimization, and therapeutic evaluation of the Leucas aspera phytosome‐based thermogel for topical antipsoriatic therapy, highlighting its enhanced solubility, skin deposition, and in vivo efficacy in an imiquimod‐induced psoriasis model. Created with BioRender.com.
Ananda Kumar Chettupalli   +2 more
wiley   +1 more source

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