Results 21 to 30 of about 469 (114)

Overview of the current use of levosimendan in France: a prospective observational cohort study [PDF]

open access: yes, 2023
Background Following the results of randomized controlled trials on levosimendan, French health authorities requested an update of the current use and side-effects of this medication on a national scale.
ARNAUD, Causeret   +47 more
core   +2 more sources

Levosimendan accelerates recovery in patients with takotsubo cardiomyopathy [PDF]

open access: yes, 2016
Background: The aim of this study was to determine the efficacy and safety of levosimendanin takotsubo cardiomyopathy (TC).Methods: The study was conducted in a retrospective design and 42 consecutive patients were enrolled in 6 cardiovascular centers in
Akyol, Aytac   +7 more
core   +2 more sources

Effect of levosimendan in experimental verapamil- induced myocardial depression [PDF]

open access: yes, 2010
Background: Calcium antagonist overdose can cause severe deterioration of hemodynamics unresponsible to treatment with beta adrenergic inotropes. The aim of the study was to evaluate in an experimental model the effects of levosimendan during severe ...
Kiviniemi, Vesa   +6 more
core   +4 more sources

Assessment of sustained effects of levosimendan and dobutamine on left ventricular systolic functions by using novel tissue Doppler derived indices in patients with advanced heart failure [PDF]

open access: yes, 2015
Background: Previous studies comparing levosimendan vs. dobutamine have revealed that levosimendan is better in relieving symptoms. Echocardiographic studies have been done using second measurements immediately following a dobutamine infusion or while it
Akturk, Ibrahim Faruk   +9 more
core   +2 more sources

Nanochanneled Device and Related Methods [PDF]

open access: yes, 2013
A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device.
Ferrari, Mauro   +7 more
core   +5 more sources

Rationale, experimental data, and emerging clinical evidence on early and preventive use of levosimendan in patients with ventricular dysfunction [PDF]

open access: yes, 2020
Acute ventricular dysfunction (AVD) is a complex condition with substantial morbidity and mortality, still featuring unique therapeutic challenges. Levosimendan is a calcium sensitizer and ATP-dependent potassium channel opener that was developed as an ...
Agostoni P.   +5 more
core   +1 more source

Use of levosimendan in acute heart failure [PDF]

open access: yes, 2018
Peer ...
Giannakoulas, George   +8 more
core   +1 more source

The inodilator levosimendan: 20 years of experience in various settings of cardiac care [PDF]

open access: yes, 2020
Levosimendan emerged in the 1990s as a first-in-class inotrope and vasodilator that enhances cardiac contractility by sensitizing the contractile response to cardiac troponin C and causes vasodilatation by opening potassium-dependent ATP channels on ...
Grossini, Elena   +2 more
core   +2 more sources

The Effectiveness of Levosimendan on Veno-Arterial Extracorporeal Membrane Oxygenation Management and Outcome: A Systematic Review and Meta-Analysis [PDF]

open access: yes, 2021
Objectives: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) provides a temporary support system for patients with cardiogenic shock refractory to conventional medical therapies.
Alkhulaifi, A. (Abdulaziz)   +7 more
core   +3 more sources

Levosimendan Administration in Limb Ischemia: Multicomponent Signaling Serving Kidney Protection [PDF]

open access: yes, 2016
AIMS AND OBJECTIVES: Acute renal failure is a severe complication of lower extremity major arterial reconstructions, which could even be fatal. Levosimendan is a dual-acting positive inotropic and vasodilatory agent, which is suspected to have protective
A Morelli   +50 more
core   +3 more sources

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