Overview of the current use of levosimendan in France: a prospective observational cohort study [PDF]
, 2023 Background Following the results of randomized controlled trials on levosimendan, French health authorities requested an update of the current use and side-effects of this medication on a national scale.
ARNAUD, Causeret +47 more
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Levosimendan accelerates recovery in patients with takotsubo cardiomyopathy [PDF]
, 2016 Background: The aim of this study was to determine the efficacy and safety of levosimendanin takotsubo cardiomyopathy (TC).Methods: The study was conducted in a retrospective design and 42 consecutive patients were enrolled in 6 cardiovascular centers in
Akyol, Aytac +7 more
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Nanochanneled Device and Related Methods [PDF]
, 2013 A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device.
Ferrari, Mauro +7 more
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Assessment of sustained effects of levosimendan and dobutamine on left ventricular systolic functions by using novel tissue Doppler derived indices in patients with advanced heart failure [PDF]
, 2015 Background: Previous studies comparing levosimendan vs. dobutamine have revealed that levosimendan is better in relieving symptoms. Echocardiographic studies have been done using second measurements immediately following a dobutamine infusion or while it
Akturk, Ibrahim Faruk +9 more
core +2 more sources
Rationale, experimental data, and emerging clinical evidence on early and preventive use of levosimendan in patients with ventricular dysfunction [PDF]
, 2020 Acute ventricular dysfunction (AVD) is a complex condition with substantial morbidity and mortality, still featuring unique therapeutic challenges. Levosimendan is a calcium sensitizer and ATP-dependent potassium channel opener that was developed as an ...
Agostoni P. +5 more
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The Effectiveness of Levosimendan on Veno-Arterial Extracorporeal Membrane Oxygenation Management and Outcome: A Systematic Review and Meta-Analysis [PDF]
, 2021 Objectives: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) provides a temporary support system for patients with cardiogenic shock refractory to conventional medical therapies.
Alkhulaifi, A. (Abdulaziz) +7 more
core +3 more sources
The inodilator levosimendan: 20 years of experience in various settings of cardiac care [PDF]
, 2020 Levosimendan emerged in the 1990s as a first-in-class inotrope and vasodilator that enhances cardiac contractility by sensitizing the contractile response to cardiac troponin C and causes vasodilatation by opening potassium-dependent ATP channels on ...
Grossini, Elena +2 more
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Use of levosimendan in acute heart failure [PDF]
, 2018 Peer ...
Giannakoulas, George +8 more
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Effect of Preoperative Infusion of Levosimendan on Biomarkers of Myocardial Injury and Haemodynamics After Paediatric Cardiac Surgery: A Randomised Controlled Trial [PDF]
, 2020 Trial registry number: EudraCT 2012-005310-19.Key Points A randomised controlled trial was conducted to test the hypothesis that preoperative infusion of levosimendan would decrease myocardial injury biomarkers (troponin I and B-type natriuretic peptide)
Abril-Molina, Ana +6 more
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Levosimendan Administration in Limb Ischemia: Multicomponent Signaling Serving Kidney Protection [PDF]
, 2016 AIMS AND OBJECTIVES: Acute renal failure is a severe complication of lower extremity major arterial reconstructions, which could even be fatal. Levosimendan is a dual-acting positive inotropic and vasodilatory agent, which is suspected to have protective
A Morelli +50 more
core +3 more sources