Results 91 to 100 of about 14,059 (132)
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Immune defects in simian acquired immunodeficiency syndrome

Veterinary Immunology and Immunopathology, 1985
We recently reported a Simian Acquired Immunodeficiency Syndrome (SAIDS) in rhesus macaques at the California Primate Research Center. Here, we studied in vitro lymphocyte response to the mitogens Concanavalin A (Con A), phytohemagglutinin (PHA) and pokeweed mitogen (PWM) with and without interleukin 2 (IL-2).
D H, Maul   +6 more
openaire   +2 more sources

Functional deficiency of polymorphonuclear leukocytes in simian acquired immunodeficiency syndrome

American Journal of Veterinary Research, 1991
Summary The functional characteristics of polymorphonuclear leukocytes (pmn), considered to be the first line of host defense against infections, from rhesus macaques confirmed to have simian retrovirus (srv)-induced simian acquired immunodeficiency syndrome (saids), were evaluated.
A T, Cheung, M B, Gardner
openaire   +2 more sources

Sequence relationships of type D retroviruses which cause simian acquired immunodeficiency syndrome

Virology, 1987
Simian acquired immunodeficiency syndrome (SAIDS) in macaque monkeys is caused by type D retroviruses; three independent virus isolates are identified as SRV-1 (SAIDS retrovirus-serotype 1), SRV-2, and MPMV (Mason-Pfizer monkey virus). Virions from these three isolates have serologically related core antigens, but distinct surface proteins. Also, SRV-2
R M, Thayer   +5 more
openaire   +2 more sources

Transmission of Simian Acquired Immunodeficiency Syndrome (SAIDS) with Blood or Filtered Plasma

Science, 1984
Simian acquired immunodeficiency syndrome (SAIDS), a disease clinically and pathologically similar to acquired immunodeficiency syndrome in humans, was transmitted from diseased rhesus monkeys ( Macaca mulatta ) to normal monkeys by inoculation with heparinized whole blood or plasma that had been passed through ...
Maneth Gravell   +12 more
openaire   +2 more sources

Transmission of simian acquired immunodeficiency syndrome with a type D retrovirus: Immunological aspects

Clinical Immunology and Immunopathology, 1986
Simian acquired immunodeficiency syndrome (SAIDS) was transmitted to four of four rhesus macaques with blood from rhesus macaques naturally infected with a type D retrovirus, simian retrovirus-2 (SRV-2). Three of the four blood recipients died with SAIDS at 13, 15, and 26 weeks postinoculation. The fourth animal is alive with SAIDS.
B J, Wilson   +5 more
openaire   +2 more sources

EXPERIMENTAL TRANSMISSION OF SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME (SAIDS) AND KAPOSI-LIKE SKIN LESIONS

The Lancet, 1983
A disease that is similar to human AIDS may occur in monkeys. Simian AIDS (SAIDS) was experimentally transmitted from 2 rhesus monkeys dying of the disease to 4 cytomegalovirus (CMV) antibody-negative rhesus monkeys. The inocula consisted of the supernatant fluid from 10% homogenates of various tissues with or without buffy-coat cells from blood ...
W T, London   +9 more
openaire   +2 more sources

Proliferation and Apoptosis-Related Gene Expression in Experimental Acquired Immunodeficiency Syndrome-Related Simian Lymphoma

Blood, 1999
Abstract Lymphomas in 10 cynomolgus monkeys infected with a simian immunodeficiency virus (SIVsm) were studied with regard to proliferative activity and apoptosis-related gene expression. All were diffuse large-cell lymphomas, showed mono or oligoclonality and a 9/10 diploid cellular DNA content.
E, Castaños-Vélez   +5 more
openaire   +2 more sources

Severe pulmonary pneumocystosis in simian acquired immunodeficiency syndrome induced by simian immunodeficiency virus: its characterization by the polymerase-chain-reaction method and failure of experimental transmission to immunodeficient animals

Parasitology Research, 1993
Pneumocystis carinii (Pc) infection was observed in three of five rhesus monkeys infected with simian immunodeficiency virus (SIVmac251). They showed severe symptoms similar to those associated with human acquired immunodeficiency syndrome (AIDS). Histopathology revealed severe pulmonary pneumocystosis in one of three Pc-positive monkeys, and anti-Pc ...
T, Furuta   +8 more
openaire   +2 more sources

Neutralizing antibody in Celebes black macaques recovering from infection with simian acquired immunodeficiency syndrome retrovirus type 2

Clinical Immunology and Immunopathology, 1986
Neutralizing antibodies that block the ability of simian acquired immunodeficiency syndrome (SAIDS) retrovirus type 2 (SRV-2) to induce syncytium formation in cultures of Raji cells have been found in the serum of nonviremic Celebes black macaques (Macaca nigra). Serum from Celebes macaques that are viremic have little or no neutralizing activity.
S M, Shiigi   +6 more
openaire   +2 more sources

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