Results 1 to 10 of about 27,759 (187)

The default mode network is affected in the early stage of simian immunodeficiency virus infection: a longitudinal study [PDF]

Neural Regeneration Research, 2023
Acquired immune deficiency syndrome infection can lead to cognitive dysfunction represented by changes in the default mode network. Most recent studies have been cross-sectional and thus have not revealed dynamic changes in the default mode network ...
Zhen-Chao Tang, Jiao-Jiao Liu, Xue-Tong Ding, Dan Liu, Hong-Wei Qiao, Xiao-Jie Huang, Hui Zhang, Jie Tian, Hong-Jun Li   +8 more
doaj   +2 more sources

Simian Immunodeficiency Virus: A Model for NeuroAIDS

Neurobiology of Disease, 1997
In addition to its profound effects on the immune system, HIV also infects the CNS and can cause abnormalities in infected individuals ranging from mild cognitive and motor disorders to frank dementia.
Howard S. Fox, Lisa H. Gold, Steven J. Henriksen, Floyd E. Bloom   +3 more
doaj   +3 more sources

Advances in SIV/SHIV Non-Human Primate Models of NeuroAIDS

Pathogens, 2021
Non-human primates (NHPs) are the most relevant model of Acquired Immunodeficiency Syndrome (AIDS) and neuroAIDS, being of great importance in explaining the pathogenesis of HIV-induced nervous system damage.
Sonia Moretti, Sara Virtuoso, Leonardo Sernicola, Stefania Farcomeni, Maria Teresa Maggiorella, Alessandra Borsetti   +5 more
doaj   +1 more source

SIV/SHIV-Zika co-infection does not alter disease pathogenesis in adult non-pregnant rhesus macaque model. [PDF]

PLoS Neglected Tropical Diseases, 2018
Due to the large geographical overlap of populations exposed to Zika virus (ZIKV) and human immunodeficiency virus (HIV), understanding the disease pathogenesis of co-infection is urgently needed.
Mehdi R M Bidokhti, Debashis Dutta, Lepakshe S V Madduri, Shawna M Woollard, Robert Norgren, Luis Giavedoni, Siddappa N Byrareddy   +6 more
doaj   +1 more source

Rev proteins of human and simian immunodeficiency virus enhance RNA encapsidation. [PDF]

PLoS Pathogens, 2007
The main function attributed to the Rev proteins of immunodeficiency viruses is the shuttling of viral RNAs containing the Rev responsive element (RRE) via the CRM-1 export pathway from the nucleus to the cytoplasm.
Sabine Brandt, Maik Blissenbach, Bastian Grewe, Rebecca Konietzny, Thomas Grunwald, Klaus Uberla   +5 more
doaj   +1 more source

Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection. [PDF]

PLoS ONE, 2011
A safe, efficacious vaccine is required to stop the AIDS pandemic. Disappointing results from the STEP trial implied a need to include humoral anti-HIV-1 responses, a notion supported by RV144 trial data even though correlates of protection are unknown ...
Samir K Lakhashe, Wendy Wang, Nagadenahalli B Siddappa, Girish Hemashettar, Patricia Polacino, Shiu-Lok Hu, François Villinger, James G Else, Francis J Novembre, John K Yoon, Sandra J Lee, David C Montefiori, Ruth M Ruprecht, Robert A Rasmussen   +13 more
doaj   +1 more source

Evolution of a Simian Immunodeficiency Virus Pathogen [PDF]

Journal of Virology, 1998
ABSTRACTAnalysis of disease induction by simian immunodeficiency viruses (SIV) in macaques was initially hampered by a lack of molecularly defined pathogenic strains. The first molecularly cloned SIV strains inoculated into macaques, SIVmacBK28 and SIVmacBK44 (hereafter designated BK28 and BK44, respectively), were cases in point, since they failed to ...
P, Edmonson, M, Murphey-Corb, L N, Martin, C, Delahunty, J, Heeney, H, Kornfeld, P R, Donahue, G H, Learn, L, Hood, J I, Mullins   +9 more
openaire   +2 more sources

Simian Immunodeficiency Virus Infection of Chimpanzees [PDF]

Journal of Virology, 2005
(Uploaded by Plazi for the Bat Literature Project) Simian immunodeficiency viruses (SIVs) are primate lentiviruses that infect no fewer than 36 different nonhuman primate species in sub-Saharan Africa ([4][1], [9][2], [62][3]). Two of these viruses, SIVcpz from chimpanzees ( Pan troglodytes ) and SIVsmm from sooty mangabeys ( Cercocebus atys ...
Paul M, Sharp, George M, Shaw, Beatrice H, Hahn   +2 more
openaire   +3 more sources

Unique Pattern of Enzootic Primate Viruses in Gibraltar Macaques

Emerging Infectious Diseases, 2008
Because Gibraltar's macaques (Macaca sylvanus) have frequent contact with humans, we assayed 79 macaques for antibodies to enzootic primate viruses. All macaques were seronegative for herpesvirus B, simian T-cell lymphotropic virus, simian retrovirus ...
Gregory A. Engel, Mark Pizarro, Eric Shaw, John Cortes, Agustin Fuentes, Peter A. Barry, Nicholas Lerche, Richard Grant, Douglas Cohn, Lisa Jones-Engel   +9 more
doaj   +1 more source

Nonpathogenic Simian Immunodeficiency Virus Infections [PDF]

Cold Spring Harbor Perspectives in Medicine, 2011
The simian immunodeficiency viruses (SIVs) are a diverse group of viruses that naturally infect a wide range of African primates, including African green monkeys (AGMs) and sooty mangabey monkeys (SMs). Although natural infection is widespread in feral populations of AGMs and SMs, this infection generally does not result in immunodeficiency.
Nichole R, Klatt, Guido, Silvestri, Vanessa, Hirsch   +2 more
openaire   +2 more sources