Results 21 to 30 of about 27,759 (187)

Common Themes of Antibody Maturation to Simian Immunodeficiency Virus, Simian-Human Immunodeficiency Virus, and Human Immunodeficiency Virus Type 1 Infections [PDF]

Journal of Virology, 1998
ABSTRACTCharacterization of virus-specific immune responses to human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) is important to understanding the early virus-host interactions that may determine the course of virus infection and disease.
K S, Cole, M, Murphey-Corb, O, Narayan, S V, Joag, G M, Shaw, R C, Montelaro   +5 more
openaire   +2 more sources

A macaque model to study vaginal HSV-2/immunodeficiency virus co-infection and the impact of HSV-2 on microbicide efficacy. [PDF]

PLoS ONE, 2009
Herpes simplex virus type-2 (HSV-2) infection enhances the transmission and acquisition of human immunodeficiency virus (HIV). This occurs in symptomatic and asymptomatic stages of HSV-2 infection, suggesting that obvious herpetic lesions are not ...
Federica Crostarosa, Meropi Aravantinou, Onome J Akpogheneta, Edith Jasny, Andrew Shaw, Jessica Kenney, Michael Piatak, Jeffrey D Lifson, Aaron Teitelbaum, Lieyu Hu, Anne Chudolij, Thomas M Zydowsky, James Blanchard, Agegnehu Gettie, Melissa Robbiani   +14 more
doaj   +1 more source

Association of MHC-I genotypes with disease progression in HIV/SIV infections

Frontiers in Microbiology, 2012
Virus-specific cytotoxic T lymphocytes (CTLs) are major effectors in acquired immune　responses against viral infection. Virus-specific CTLs recognize specific viral peptides　presented by major histocompatibility complex-class I (MHC-I) on the surface of ...
Takushi eNomura, Takushi eNomura, Tetsuro eMatano, Tetsuro eMatano   +3 more
doaj   +1 more source

The nef gene of simian immunodeficiency virus SIVmac1A11 [PDF]

Journal of Virology, 1992
The role of the simian immunodeficiency virus (SIV) nef gene in viral replication was investigated in several tissue culture systems. SIVmac1A11 is a molecularly cloned virus which replicates in both peripheral blood mononuclear cells (PBMC) and macrophages, although no disease is observed in infected rhesus macaques.
R E, Unger, M L, Marthas, E, Pratt-Lowe, P A, Padrid, P A, Luciw   +4 more
openaire   +2 more sources

Development of a progressive HIV-1-Like infection model in northern pig-tailed macaques using stHIV-1sv/G53D

Emerging Microbes and Infections
Simian immunodeficiency virus (SIV) and simian-human immunodeficiency virus (SHIV) infections in nonhuman primates closely approximate human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), but intrinsic viral differences limit ...
Tian-Zhang Song, Qing Li, Li-Rong Zhang, Yan Hu, Ying Lu, Yong-Tang Zheng   +5 more
doaj   +1 more source

The significance of a common idiotype (1F7) on antibodies against human immune deficiency virus type 1 and hepatitis C virus

Frontiers in Oncology, 2016
In this review, we trace the concept and potential functional role of regulatory idiotypes in the immune response to human immunodeficiency virus type 1 (HIV-1), simian immunodeficiency virus, and hepatitis C virus (HCV).
Sybille eMuller, Matthew S Parsons, Heinz eKohler, Michael eGrant   +3 more
doaj   +1 more source

The Secretion of IL-22 from Mucosal NKp44+ NK Cells Is Associated with Microbial Translocation and Virus Infection in SIV/SHIV-Infected Chinese Macaques

Journal of Immunology Research, 2014
Microbial translocation (MT) causes systemic immune activation in chronic human immunodeficiency virus (HIV) infection. The role of a novel subtype of innate lymphoid cells, the NKp44+ NK cells, in HIV/simian immunodeficiency virus- (SIV-) induced MT ...
Wei Wang, Fangxin Wu, Zhe Cong, Kejian Liu, Chuan Qin, Qiang Wei   +5 more
doaj   +1 more source

Susceptibilities of Simian Immunodeficiency Virus to Protease Inhibitors [PDF]

Antimicrobial Agents and Chemotherapy, 2003
ABSTRACT We used a focal infectivity assay with HeLa H1-JC.37 cells to directly compare susceptibilities of simian immunodeficiency virus (SIV) and human immunodeficiency virus type 1 (HIV-1) to protease inhibitors. SIVmac239 was inhibited by indinavir, saquinavir, and ritonavir, with 50% effective concentrations (means ± standard deviations)
Angelica C, Giuffre, Joanne, Higgins, Robert W, Buckheit, Thomas W, North   +3 more
openaire   +2 more sources

HIV incidence and correlates of incident infection among Brazilian blood donors following adoption of individual donor assessment

Vox Sanguinis, EarlyView.
Abstract Background and Objectives In 2020, Brazil implemented individual donor assessment (IDA), expanding eligibility to include individuals previously deferred, such as men who have sex with men (MSM). We assessed human immunodeficiency virus (HIV) incidence and correlates of incident infection among blood donors following this policy change ...
Renata Buccheri, Eduard Grebe, Donald E. Warden, Carolina Miranda, Ligia Capuani, Cecilia S. Alencar, Luiz Amorim, Cesar de Almeida‐Neto, Maisa Ribeiro, Paula Loureiro, Nelson Fraiji, Clara Di Germanio, Leilani Montalvo, Jennifer Leddy, Mars Stone, Ester C. Sabino, Brian Custer, the Recipient Epidemiology and Donor Evaluation Study‐IV‐Pediatric (REDS‐IV‐P)   +17 more
wiley   +1 more source

Simian Foamy Virus Co-Infections

Viruses, 2019
Foamy viruses (FVs), also known as spumaretroviruses, are complex retroviruses that are seemingly nonpathogenic in natural hosts. In natural hosts, which include felines, bovines, and nonhuman primates (NHPs), a large percentage of adults are infected ...
Shannon M. Murray, Maxine L. Linial
doaj   +1 more source