Results 31 to 40 of about 27,759 (187)

Frequent first-trimester pregnancy loss in rhesus macaques infected with African-lineage Zika virus.

open access: yesPLoS Pathogens, 2023
In the 2016 Zika virus (ZIKV) pandemic, a previously unrecognized risk of birth defects surfaced in babies whose mothers were infected with Asian-lineage ZIKV during pregnancy.
Jenna R Rosinski   +39 more
doaj   +1 more source

CD49a expression defines a metabolically robust, cytokine‐biased liver NK cell subset in rhesus macaques during lentivirus infection

open access: yesImmunology &Cell Biology, Volume 104, Issue 7, Page 656-666, August 2026.
Liver‐resident NK cells (CD49a+ NK cells) in rhesus macaques display distinct activating receptor and metabolic markers enhanced phenotype compared with hepatic NK cell subsets (CD49a−) in the liver. These cells exhibit heightened cytokine polyfunctionality with restrained cytotoxic responses upon mitogen stimulation in comparison with CD49a− NK cell ...
Andrew Hudson   +4 more
wiley   +1 more source

Central African Hunters Exposed to Simian Immunodeficiency Virus

open access: yesEmerging Infectious Diseases, 2005
HIV-seronegative Cameroonians with exposure to nonhuman primates were tested for simian immunodeficiency virus (SIV) infection.
Marcia L. Kalish   +12 more
doaj   +1 more source

Epidemiological Survey and Risk Factor Analysis of 14 Potential Pathogens in Golden Snub-Nosed Monkeys at Shennongjia National Nature Reserve, China

open access: yesPathogens, 2023
Golden snub-nosed monkeys (Rhinopithecus roxellanae) belong to Class A, the highest level of endangered primate species. Exploring the infection status of potential pathogens in golden snub-nosed monkeys is important for controlling associated diseases ...
Mingpu Qi   +14 more
doaj   +1 more source

Phenotypic profiling of pristane‐induced mimicking human systemic lupus erythematosus in Macaca fascicularis

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 7, Page 1302-1309, July 2026.
Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny   +12 more
wiley   +1 more source

Divergent HIV and Simian Immunodeficiency Virus Surveillance, Zaire

open access: yesEmerging Infectious Diseases, 2005
Recent HIV infection or divergent HIV or simian immunodeficiency virus (SIV) strains may be responsible for Western blot–indeterminate results on 70 serum samples from Zairian hospital employees that were reactive in an enzyme immunoassay.
Amanda Schaefer   +7 more
doaj   +1 more source

Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Infectious diseases can disrupt endocrine homeostasis through direct cytopathic injury, autoimmune dysregulation, or pathogen‐derived hormone‐like effects. Viruses and bacteria are the most frequent agents, whereas fungi and parasites contribute less commonly, even remaining clinically relevant, especially in the immunocompromised population.
Francesco Capoccia   +4 more
wiley   +1 more source

Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control

open access: yesNature Communications, 2019
Here, the authors compare gene expression signatures in rectal tissues of African green monkeys (AGMs) and rhesus macaques (RMs) acutely infected with simian immunodeficiency virus and find that AGMs rapidly activate and maintain evolutionarily conserved
Fredrik Barrenas   +23 more
doaj   +1 more source

CRISPR/Cas9 genome editing to create nonhuman primate models for studying stem cell therapies for HIV infection

open access: yesRetrovirology, 2022
Nonhuman primates (NHPs) are well-established basic and translational research models for human immunodeficiency virus (HIV) infections and pathophysiology, hematopoietic stem cell (HSC) transplantation, and assisted reproductive technologies.
Jenna Kropp Schmidt   +3 more
doaj   +1 more source

CD8+ Tissue‐Resident Memory T Cells in Health and Disease

open access: yesMedComm, Volume 7, Issue 7, July 2026.
CD8+ TRM cells are at the center of immunity, mediating potent local innate and adaptive immune responses. While TRM cells mediate protective immunity against infections and tumors, they also contribute to pathological inflammation in autoimmune conditions.
Yu‐Han Ai   +13 more
wiley   +1 more source

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