Results 51 to 60 of about 89 (88)

Use of Simian Immunodeficiency Virus for Vaccine Research

Journal of Medical Primatology, 1990
Rhesus monkeys were immunized with purified, disrupted, noninfectious simian immunodeficiency virus (SIV) in adjuvant induced SIV neutralizing antibodies. Two of six previously vaccinated macaques were protected against infection when challenged with 200–1,000 animal infectious doses of uncloned, pathogenic SIV and both have remained free of signs of ...
Norval W. King, Douglas J. Ringler, D K Schmidt, Muthiah D. Daniel, Toshiaki Kodama, Ronald C. Desrosiers, Michael S. Wyand, Prabhat K. Sehgal, Cynthia D. Troup   +8 more
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Pathogenic mechanisms in simian immunodeficiency virus infection

Current Opinion in HIV and AIDS, 2008
Recent work in pathogenic simian immunodeficiency (SIV) infection of Asian macaques and in natural, nonpathogenic SIV infections of African nonhuman primate species has demonstrated that persistent activation has profound effects on CD4+ memory T-cell proliferation, differentiation and survival.
Zvi Grossman, Louis J. Picker
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Cytotoxic T lymphocytes specific for the simian immunodeficiency virus

Immunological Reviews, 1999
Summary: A non‐human primate model for acquired immunodeficiency syndrome (AIDS), the simian immunodeficiency virus (SIV)‐infected rhesus monkey, was used to explore the role of the AIDS virus‐specific cytotoxic T‐lymphocyce (CTL) response in disease pathogenesis.
Keith A. Reimann, Aruna Seth, Vanessa M. Hirsch, Holly L. Jordan, Norman L. Letvin, Marcelo I. Kuroda, Jörn E. Schmitz   +6 more
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Mucosal Transmission of Simian Immunodeficiency Virus

1994
Although human immunodeficiency virus (HIV) is transmitted primarily by heterosexual contact very little is understood about the biology of heterosexual transmission of HIV. Epidemiological studies indicate that HIV is not efficiently transmitted by sexual contact. In fact many other sexually transmitted diseases (STDs) are more efficiently transmitted.
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The biology and immunopathology of simian immunodeficiency virus infection

Current Opinion in Immunology, 1990
Since the initial report (Daniel et al, Science 1985, 228:1201-1204) of the isolation of a lentivirus that was related to the human immunodeficiency virus (HN) from rhesus macaque monkeys (Mucucu mukztta) and the subsequent demonstration that experimental infection of macaques with this virus resulted in an acquired immunodeficiency syndrome (AIDS ...
P.N. Fultz, D.C. Anderson
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Histopathological changes in simian immunodeficiency virus infection

The Journal of Pathology, 1990
AbstractThe histological lesions were studied in seven rhesus and three cynomolgus monkeys infected with simian immunodeficiency virus for periods ranging from nine weeks to 18 months. Lymphoreticular changes included hyperplasia, follicular involution and depletion, and one animal had amyloidosis of the spleen.
E. J. Stott, E. J. Stott, M. J. Dennis, Nancy R. Cook, R. W. Cook, A. Baskerville, P. J. Greenaway, P. A. Kitchin, P. A. Kitchin, Martin Cranage, A. Ramsay, A. Ramsay   +11 more
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Simian Immunodeficiency Virus Infections

1993
African species of nonhuman primates harboring persistent simian immunodeficiency virus (SIV) infections do not develop clinical illness or gross lesions. These species include: African green monkeys infected with SIVAGM, sooty mangabey monkeys infected with SIVSMM(δ), Sykes’ monkeys infected with SIVSYK; mandrills infected with SIVMND, and chimpanzees
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Simian immunodeficiency virus mac251 infection of astrocytes

Journal of Neurovirology, 2000
Human immunodeficiency virus type 1 (HIV-1) infection of astrocytes has been demonstrated in the brains of patients with AIDS dementia complex (ADC) and may play an important role in neuropathological pathways of HIV-related encephalopathy. SIVmac-infected monkeys develop an acquired immunodeficiency syndrome (AIDS) with CNS involvement which is quite ...
Martine Franck-Duchenne, Frangois D Boussin, Gilles J. Guillemin, Dominique Dormont, Roger Le Grand, Juliana Croitoru   +5 more
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CD4+ T Cell Responses to Simian Immunodeficiency Virus

1994
T cells have classically been divided into two populations on the basis of their surface phenotype, MHC restriction and function. CD8+ T cells recognize endogenous antigen in association with MHC class I molecules and display cytotoxic activity against infected or peptide-pulsed target cells.
Kingston H. G. Mills, W. C. Jones
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Comparison of simian immunodeficiency virus and human immunodeficiency virus encephalitides in the immature host

Annals of Neurology, 1988
The simian immunodeficiency virus (SIV) is closely related to the human immunodeficiency virus (HIV) in genomic organization and morphology. More important, SIV and HIV are both primate lentiviruses that cause transmissible immunodeficiency and encephalitis, with an apparently increased virulence in the immature host.
Michael Murphey-Corb, Leroy R. Sharer, Eun-Sook Cho, Gary B. Baskin, Leon G. Epstein, Benjamin M. Blumberg   +5 more
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