Results 51 to 60 of about 218,831 (262)

Association of MHC-I genotypes with disease progression in HIV/SIV infections

Frontiers in Microbiology, 2012
Virus-specific cytotoxic T lymphocytes (CTLs) are major effectors in acquired immune　responses against viral infection. Virus-specific CTLs recognize specific viral peptides　presented by major histocompatibility complex-class I (MHC-I) on the surface of ...
Takushi eNomura, Takushi eNomura, Tetsuro eMatano, Tetsuro eMatano   +3 more
doaj   +1 more source

Conserved presence of G-quadruplex forming sequences in the Long Terminal Repeat Promoter of Lentiviruses [PDF]

, 2017
G-quadruplexes (G4s) are secondary structures of nucleic acids that epigenetically regulate cellular processes. In the human immunodeficiency lentivirus 1 (HIV-1), dynamic G4s are located in the unique viral LTR promoter.
A Ayouba, A Henderson, A Rambaut, AK Todd, AM Fleming, AN Lane, AR Haeusler, B Berkhout, B Zhou, BF Keele, D Piekna-Przybylska, D Qu, D Rhodes, D Sen, DJ Patel, E Tosoni, EA Raiber, F Barre-Sinoussi, F Benachenhou, F Bibollet-Ruche, F Heuverswyn Van, F Turrini, G Biffi, GE Crooks, IT Holder, J Felsenstein, J Norseen, J Qiu, J Song, J Yamaguchi, JE Clements, JF Fisette, JP Taylor, K Tamura, K Tluckova, KA Jones, LA Pereira, M Fry, M Metifiot, M Sala, M Scalabrin, MA Larkin, N Maizels, ND Perkins, NH Campbell, P Fratta, P Ivanov, P Murat, P Sket, R Perrone, R Perrone, R Perrone, R Perrone, RC Edgar, RC Gallo, RJ Gifford, S Amrane, S Artusi, S Artusi, S Balasubramanian, S Bhatia, S Broos, S Burge, S Pohlmann, SE Tong-Starksen, SR Wang, SR Wang, Y Wang   +67 more
core   +1 more source

Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding [PDF]

, 2016
The surface envelope glycoprotein (SU) of Human immunodeficiency virus type 1 (HIV-1), gp120SU plays an essential role in virus binding to target CD4+ T-cells and is a major vaccine target.
Bess, JW, Binet, D, Bouché, L, Canis, K, Chertova, E, Dell, A, Desrosiers, RC, Haslam, SM, Keele, BF, Lifson, JD, Morris, HR, North, SJ, O'Connor, MJ, Pang, PC, Panico, M, Rahman, D   +15 more
core   +1 more source

T cell receptor V beta repertoire in an acute infection of rhesus monkeys with simian immunodeficiency viruses and a chimeric simian- human immunodeficiency virus

Journal of Experimental Medicine, 1995
Changes in T cell receptor (TCR) V beta repertoire and their correlation with virologic events were investigated in rhesus monkeys after acute infection with the simian immunodeficiency virus (SIV).
Zheng W. Chen, Z. Kou, C. Lekutis, Ling Shen, Dejiang Zhou, M. Halloran, John Li, Joseph G. Sodroski, D. Lee‐Parritz, N. Letvin   +9 more
semanticscholar   +1 more source

The Secretion of IL-22 from Mucosal NKp44+ NK Cells Is Associated with Microbial Translocation and Virus Infection in SIV/SHIV-Infected Chinese Macaques

Journal of Immunology Research, 2014
Microbial translocation (MT) causes systemic immune activation in chronic human immunodeficiency virus (HIV) infection. The role of a novel subtype of innate lymphoid cells, the NKp44+ NK cells, in HIV/simian immunodeficiency virus- (SIV-) induced MT ...
Wei Wang, Fangxin Wu, Zhe Cong, Kejian Liu, Chuan Qin, Qiang Wei   +5 more
doaj   +1 more source

The significance of a common idiotype (1F7) on antibodies against human immune deficiency virus type 1 and hepatitis C virus

Frontiers in Oncology, 2016
In this review, we trace the concept and potential functional role of regulatory idiotypes in the immune response to human immunodeficiency virus type 1 (HIV-1), simian immunodeficiency virus, and hepatitis C virus (HCV).
Sybille eMuller, Matthew S Parsons, Heinz eKohler, Michael eGrant   +3 more
doaj   +1 more source

HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection. [PDF]

, 2017
Antiviral innate host defenses against acute viral infections include suppression of host protein synthesis to restrict viral protein production.
Clarissa Santos Rocha, Erica A. Mendes, George R. Thompson, Guochun Jiang, Joseph K. Wong, Lauren A. Hirao, Ruth Ruprecht, Satya Dandekar, Vinayaka R. Prasad, Yuyang Tang   +9 more
core   +2 more sources

Evolution of a Simian Immunodeficiency Virus Pathogen [PDF]

Journal of Virology, 1998
ABSTRACTAnalysis of disease induction by simian immunodeficiency viruses (SIV) in macaques was initially hampered by a lack of molecularly defined pathogenic strains. The first molecularly cloned SIV strains inoculated into macaques, SIVmacBK28 and SIVmacBK44 (hereafter designated BK28 and BK44, respectively), were cases in point, since they failed to ...
P, Edmonson, M, Murphey-Corb, L N, Martin, C, Delahunty, J, Heeney, H, Kornfeld, P R, Donahue, G H, Learn, L, Hood, J I, Mullins   +9 more
openaire   +2 more sources

An investigation of the breadth of neutralising antibody response in cats naturally infected with feline immunodeficiency virus [PDF]

, 2015
Neutralising antibodies (NAbs) are believed to comprise an essential component of the protective immune response induced by vaccines against FIV and HIV infections.
Beczkowski, Pawel, Hosie, Margaret J., Litster, Annette, Logan, Nicola, McMonagle, Elizabeth, Willett, Brian J.   +5 more
core   +2 more sources

Central African Hunters Exposed to Simian Immunodeficiency Virus

Emerging Infectious Diseases, 2005
HIV-seronegative Cameroonians with exposure to nonhuman primates were tested for simian immunodeficiency virus (SIV) infection.
Marcia L. Kalish, Nathan D. Wolfe, Clement B. Ndongmo, Janet McNicholl, Kenneth E. Robbins, Michael Aidoo, Peter N. Fonjungo, George Alemnji, Clement Zeh, Cyrille F. Djoko, Eitel Mpoudi-Ngole, Donald S. Burke, Thomas M. Folks   +12 more
doaj   +1 more source