Results 91 to 100 of about 1,252,233 (299)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Pengelompokan UMKM Batik Madura Menggunakan Metode K-Means dan Sillhoutte Coefficient
TeknikaUMKM merupakan salah satu sektor pendukung perekonomian di Indonesia. UMKM Batik Madura memberikan kontribusi yang cukup tinggi terhadap penyerapan tanaga kerja dan peningkatan ekonomi masyarakat daerah. Hal ini terbukti pada penyerapan tenaga kerja UMKM
Yeni Kustiyahningsih +2 more
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Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Semi-Supervised Medical Image Classification with Pseudo Labels Using Coalition Similarity Training
MathematicsThe development of medical image classification models necessitates a substantial number of labeled images for model training. In real-world scenarios, sample sizes are typically limited and labeled samples often constitute only a small portion of the ...
Kun Liu, Shuyi Ling, Sidong Liu
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Similarity/Dissimilarity Analysis of Protein Sequences Based on a New Spectrum-Like Graphical Representation [PDF]
, 2014 Yuhua Yao +6 more
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Lingvistika tropov: shodstva i različiâ v nacionačʺnyh stilâh
Stylistyka, 2020 Based on the materials o f the works of the Belarusian writer Vladimir Korotkevich and their translauons into Russian, the problems of linguistic organization o f tropes are consiucred, their generating features o f the idiostyle and creative manner o f ...
Viktor I. Ivčenkov
doaj